Duodart 0.5mg/0.4mg Capsule
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Overview
Duodart 0.5mg/0.4mg Capsule contains dutasteride and tamsulosin 0.5mg/0.4mg, a combination medicine used to treat the symptoms of benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland that can cause urinary difficulties.
Dutasteride, a 5-alpha reductase inhibitor, gradually shrinks the enlarged prostate over time, while tamsulosin, an alpha-1 blocker, relaxes the muscles around the bladder neck and prostate for faster relief of urinary flow symptoms – together they provide both longer-term and quicker symptom control.
How it Works
Dutasteride blocks both types of 5-alpha reductase enzyme, reducing the conversion of testosterone to dihydrotestosterone (DHT), the hormone primarily responsible for prostate growth, leading to a gradual reduction in prostate size. Tamsulosin blocks alpha-1 receptors in the smooth muscle of the prostate and bladder neck, relaxing these muscles to ease urine flow.
Directions for Use
Take Duodart 0.5mg/0.4mg Capsule whole, about 30 minutes after the same meal each day, without chewing, crushing, or opening the capsule, as contact with the contents may irritate the mouth and throat. Women who are or could become pregnant should not handle leaking or damaged capsules, as dutasteride can be absorbed through the skin and may harm a male fetus.
Dosage
The usual dose of Duodart 0.5mg/0.4mg Capsule is one capsule daily, taken at around the same time each day. Your doctor will confirm this is the appropriate dose for you and will advise on how long treatment should continue, as noticeable improvement can take several weeks to months to appear.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Decreased libido (sex drive)
- Erectile dysfunction
- Breast tenderness or enlargement
- Ejaculation disorders
- Dizziness or lightheadedness
- Skin rash
Contraindications
- Known hypersensitivity to dutasteride, tamsulosin, other 5-alpha reductase inhibitors, alpha-blockers, or sulfonamides
- Severe liver impairment
- Combination with strong CYP3A4 inhibitors in patients with kidney or liver impairment (increases tamsulosin levels)
- Not for use in women or children
Drug / Food Interactions
- Other alpha-blockers should generally not be combined, as this increases the risk of low blood pressure
- PDE5 inhibitors (e.g. sildenafil, tadalafil) may increase the risk of low blood pressure when combined with the tamsulosin component
- Strong CYP3A4 inhibitors (e.g. ketoconazole) can raise tamsulosin blood levels
- Reduces PSA (prostate-specific antigen) levels by roughly half after 3-6 months – tell your doctor you are taking this medicine before any PSA test
Quick Tips
- Take at around the same time each day, about 30 minutes after the same meal
- Rise slowly from sitting or lying down, especially when starting treatment, to reduce dizziness
- Tell your doctor about this medicine before any PSA (prostate cancer screening) blood test
- Mention this medicine to your ophthalmologist before any cataract or eye surgery, due to a risk of intraoperative floppy iris syndrome
- Women who are or could be pregnant should not handle leaking or damaged capsules
- Be patient – noticeable symptom improvement can take several weeks to months
Frequently Asked Questions
What is Duodart 0.5mg/0.4mg Capsule used for?
Duodart 0.5mg/0.4mg Capsule is used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia, BPH), such as difficulty urinating, weak urine flow, and frequent urination, particularly at night.
Why does this medicine affect my PSA test results?
Dutasteride typically reduces PSA levels by about half after 3-6 months of use, even when no prostate cancer is present. Always tell your doctor you are taking this medicine before a PSA test so the result can be interpreted correctly.
Can my partner or a pregnant woman handle this medicine safely?
Women who are or could become pregnant should avoid handling leaking or damaged capsules, as dutasteride can be absorbed through the skin and may harm a developing male baby. Intact capsules are generally safe to handle.
Why might I feel dizzy when standing up?
The tamsulosin component can lower blood pressure, particularly when changing position quickly, causing dizziness or light-headedness (orthostatic hypotension). This is more common when starting treatment – rise slowly from sitting or lying down.
Do I need to mention this medicine before eye surgery?
Yes. Tamsulosin has been associated with a condition called intraoperative floppy iris syndrome during cataract surgery. Inform your ophthalmologist that you are taking this medicine before any eye surgery is scheduled.
What should I do if I miss a dose of Duodart 0.5mg/0.4mg Capsule?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Duodart 0.5mg/0.4mg Capsule from DoctorOnCall?
Yes, Duodart 0.5mg/0.4mg Capsule is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Duodart 0.5mg/0.4mg Capsule according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Duodart 0.5mg/0.4mg Capsule?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Duodart 0.5mg/0.4mg Capsule cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Duodart 0.5mg/0.4mg Capsule?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Duodart 0.5mg/0.4mg Capsule?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Dutasteride and tamsulosin hydrochloride 0.5mg/0.4mg
Safety Advice
Pregnancy
This medicine is not considered safe during pregnancy and should be avoided.
Breastfeeding
This medicine is not safe during breastfeeding and should be avoided.
Kidney
Generally safe, but caution may be required in some patients.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
