Duodart 0.5mg/0.4mg Capsule

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Brand GSK
Manufacturer GSK
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

Duodart 0.5mg/0.4mg Capsule contains Dutasteride and tamsulosin hydrochloride 0.5mg/0.4mg and is available as a capsule. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Duodart 0.5mg/0.4mg Capsule are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take Duodart 0.5mg/0.4mg Capsule whole, about 30 minutes after the same meal each day, without chewing, crushing, or opening the capsule, as contact with the contents may irritate the mouth and throat. Women who are or could become pregnant should not handle leaking or damaged capsules, as dutasteride can be absorbed through the skin and may harm a male fetus.

Dosage

The usual dose of Duodart 0.5mg/0.4mg Capsule is one capsule daily, taken at around the same time each day. Your doctor will confirm this is the appropriate dose for you and will advise on how long treatment should continue, as noticeable improvement can take several weeks to months to appear.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Decreased libido (sex drive)
  • Erectile dysfunction
  • Breast tenderness or enlargement
  • Ejaculation disorders
  • Dizziness or lightheadedness
  • Skin rash

Contraindications

  • Known hypersensitivity to dutasteride, tamsulosin, other 5-alpha reductase inhibitors, alpha-blockers, or sulfonamides
  • Severe liver impairment
  • Combination with strong CYP3A4 inhibitors in patients with kidney or liver impairment (increases tamsulosin levels)
  • Not for use in women or children

Drug / Food Interactions

  • Other alpha-blockers should generally not be combined, as this increases the risk of low blood pressure
  • PDE5 inhibitors (e.g. sildenafil, tadalafil) may increase the risk of low blood pressure when combined with the tamsulosin component
  • Strong CYP3A4 inhibitors (e.g. ketoconazole) can raise tamsulosin blood levels
  • Reduces PSA (prostate-specific antigen) levels by roughly half after 3-6 months – tell your doctor you are taking this medicine before any PSA test

Quick Tips

  • Take at around the same time each day, about 30 minutes after the same meal
  • Rise slowly from sitting or lying down, especially when starting treatment, to reduce dizziness
  • Tell your doctor about this medicine before any PSA (prostate cancer screening) blood test
  • Mention this medicine to your ophthalmologist before any cataract or eye surgery, due to a risk of intraoperative floppy iris syndrome
  • Women who are or could be pregnant should not handle leaking or damaged capsules
  • Be patient – noticeable symptom improvement can take several weeks to months

Ingredients / Active Ingredients

  • Dutasteride and tamsulosin hydrochloride 0.5mg/0.4mg

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Not Safe

This medicine is not safe during breastfeeding and should be avoided.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandGSK
ManufacturerGSK
ClassificationPrescription medicine
Ingredients / Active IngredientsDutasteride
Pack Size30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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