Repatha Evolocumab 140mg/ml Solution for Injection
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Overview
Repatha Evolocumab 140mg/ml Solution for Injection is a prescription-only medicine (POM) that contains Evolocumab 140mg/mL solution for injection. It is supplied as an injection and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.
Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.
On DoctorOnCall, Repatha Evolocumab 140mg/ml Solution for Injection is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.
Directions for Use
Repatha Evolocumab 140mg/ml Solution for Injection is injected subcutaneously (under the skin) into the abdomen, thigh, or upper arm; rotate the injection site with each dose and avoid areas that are tender, bruised, red, or hard. Remove the pre-filled pen or syringe from the refrigerator and allow it to reach room temperature for about 30 minutes before injecting – do not warm it artificially (e.g. with hot water or a microwave). A doctor, nurse, or pharmacist will teach you the correct injection technique before you self-administer at home.
Dosage
Repatha Evolocumab 140mg/ml Solution for Injection is typically given as 140mg by subcutaneous injection every 2 weeks, or as 420mg (three consecutive injections) once monthly, depending on your condition and your doctor’s recommendation. This medicine is used together with a statin (and sometimes other lipid-lowering treatment) in most patients, not as a substitute for them, unless your doctor specifically advises otherwise.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store in a refrigerator (2-8°C). Do not freeze. Keep the pre-filled pen or syringe in the original carton to protect it from light. If needed, it may be kept at room temperature (up to 25°C) for a limited period as advised by your pharmacist, but once removed from the refrigerator it should not be returned to it.
Side Effects
- Injection site reactions (redness, pain, bruising, or swelling)
- Back pain
- Symptoms of upper respiratory tract infection
- Flu-like symptoms
- Serious: signs of a severe allergic reaction (rash, swelling of the face/lips/throat, difficulty breathing) require immediate medical attention
Contraindications
- Known hypersensitivity to evolocumab or any ingredient in this product
Drug / Food Interactions
- As a monoclonal antibody, evolocumab is not metabolised by liver enzymes and has minimal drug-drug interactions
- It is intended to be used together with a statin (and sometimes ezetimibe) in most patients, not as a replacement – do not stop your statin without your doctor’s advice
- No specific food interactions are expected, but continue following any dietary advice given by your doctor for cholesterol management
Quick Tips
- Keep this medicine refrigerated and let it warm to room temperature for about 30 minutes before injecting
- Rotate injection sites (abdomen, thigh, upper arm) to reduce skin irritation
- Do not stop your statin or other cholesterol medicines unless your doctor tells you to
- Attend scheduled cholesterol (lipid panel) checks to monitor your response to treatment
- Learn the proper injection technique from your healthcare provider and follow the same schedule (every 2 weeks or monthly) consistently
Frequently Asked Questions
Is Repatha Evolocumab 140mg/ml Solution for Injection a prescription medicine?
Yes. Repatha Evolocumab 140mg/ml Solution for Injection is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
What does Repatha Evolocumab 140mg/ml Solution for Injection contain?
Repatha Evolocumab 140mg/ml Solution for Injection is supplied as an injection and contains Evolocumab 140mg/mL solution for injection. The full composition is listed in the Composition section on this page and on the product packaging.
Why is there no information here about what Repatha Evolocumab 140mg/ml Solution for Injection is for?
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
How should I take Repatha Evolocumab 140mg/ml Solution for Injection?
Take it exactly as written on your prescription label. Do not increase, reduce or skip doses on your own, and do not continue beyond the period your doctor has prescribed. Practical handling steps are set out in the Directions for Use section on this page.
What should I do if I miss a dose?
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
How should I store Repatha Evolocumab 140mg/ml Solution for Injection?
Store in a refrigerator (2-8°C). Do not freeze. Keep the pre-filled pen or syringe in the original carton to protect it from light. If needed, it may be kept at room temperature (up to 25°C) for a limited period as advised by your pharmacist, but once removed from the refrigerator it should not be returned to it. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
What should I do if I notice side effects?
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Can I stop taking Repatha Evolocumab 140mg/ml Solution for Injection on my own?
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
How do I get a prescription for Repatha Evolocumab 140mg/ml Solution for Injection?
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
How long will delivery take?
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
What payment methods can I use?
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Can Repatha Evolocumab 140mg/ml Solution for Injection be delivered to Singapore?
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Is Repatha Evolocumab 140mg/ml Solution for Injection registered with the authorities?
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
Who do I contact if there is a problem with my order?
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Ingredients / Active Ingredients
- Evolocumab 140mg/mL solution for injection
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