Epilim 200mg/5ml Syrup
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Overview
Epilim 200mg/5ml Syrup contains sodium valproate 200mg/5ml, an anticonvulsant (antiepileptic) medicine also used as a mood stabiliser, formulated as an oral syrup, often used for children or those with difficulty swallowing tablets. It is used to treat various types of epilepsy (seizures) and, in some patients, bipolar disorder.
Sodium valproate is thought to work by increasing levels of the inhibitory neurotransmitter GABA in the brain and by blocking voltage-gated sodium channels, which together reduce the abnormal, excessive electrical activity in the brain that causes seizures or contributes to mood instability.
How it Works
By increasing GABA activity and blocking voltage-gated sodium channels in nerve cells, sodium valproate reduces the excessive, uncontrolled electrical signalling in the brain responsible for seizures, and helps stabilise mood in bipolar disorder.
Directions for Use
Measure the dose accurately using the oral syringe or measuring device provided – not a household spoon. Shake well before use if instructed on the label. Can be mixed with a small amount of water or juice if preferred.
Dosage
The dose of Epilim 200mg/5ml Syrup is individualised based on your seizure type, response to treatment, and blood valproate level monitoring. Treatment is usually started at a lower dose and increased gradually by your doctor. Given the careful balance needed between seizure control and the risks of this medicine (including in pregnancy), never start, stop, or adjust your dose without your specialist’s guidance.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Drowsiness or dizziness
- Nausea or vomiting
- Weight gain
- Tremors (shaking hands)
- Hair thinning or loss
- Changes in liver function tests
- Stomach pain or indigestion
Contraindications
- Known hypersensitivity to sodium valproate or any ingredient in this product
- Active liver disease or a history of severe hepatic dysfunction
- Known urea cycle disorders
- Porphyria
- Pregnancy, or the possibility of becoming pregnant, without an effective pregnancy prevention programme in place, due to the high risk of serious birth defects and developmental problems (foetal valproate syndrome) – unless no other suitable treatment is available, as assessed by a specialist
Drug / Food Interactions
- Other antiepileptics, such as lamotrigine, phenytoin, or carbamazepine, can have significant level interactions with valproate, requiring dose adjustment and monitoring
- Carbapenem antibiotics (e.g. meropenem, imipenem) can significantly reduce valproate blood levels, risking breakthrough seizures, and are generally avoided together
- Aspirin and other highly protein-bound medicines may increase free valproate levels in the blood
- Alcohol can increase sedation and add to the risk of liver-related side effects, and should be avoided or limited
Quick Tips
- Never stop or start this medicine, or change your dose, without your specialist’s guidance
- Attend all scheduled blood tests (liver function, blood counts, and valproate levels) as advised
- Women and girls of childbearing potential must discuss the pregnancy prevention programme and the risks of valproate in pregnancy with their doctor before, and while, taking this medicine
- Report unexplained vomiting, severe tiredness, loss of appetite, or abdominal pain to your doctor immediately
- Avoid alcohol while taking this medicine
- Carry a valproate alert card or similar documentation if provided by your doctor or pharmacist
Frequently Asked Questions
What is Epilim 200mg/5ml Syrup used for?
Epilim 200mg/5ml Syrup is used to treat various types of epilepsy (seizures) and, in some patients, manic episodes associated with bipolar disorder.
Is sodium valproate safe to take during pregnancy?
No. Sodium valproate carries a high risk of serious birth defects and developmental problems in an unborn baby (foetal valproate syndrome) if taken during pregnancy. Women and girls of childbearing potential should be on an effective, specialist-supervised pregnancy prevention programme, and must never stop or start this medicine around pregnancy without urgent specialist guidance, given the need to balance seizure control against these risks.
Why do I need regular blood tests while taking this medicine?
Regular blood tests monitor your liver function, blood counts, and valproate levels, helping your doctor detect rare but serious side effects early and ensure your dose remains appropriate.
Can I stop taking this medicine if my seizures are well-controlled?
No, do not stop without specialist guidance. Stopping suddenly can trigger a return of seizures or a serious withdrawal effect; any change in treatment must be planned and supervised by your specialist.
What early warning signs of liver problems should I watch for?
Contact your doctor immediately if you notice unexplained vomiting, severe lethargy, loss of appetite, or yellowing of the skin or eyes, especially within the first six months of starting treatment, as these can be early signs of a serious liver problem.
Can I buy Epilim 200mg/5ml Syrup from DoctorOnCall?
Yes, Epilim 200mg/5ml Syrup is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Epilim 200mg/5ml Syrup according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Epilim 200mg/5ml Syrup?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Epilim 200mg/5ml Syrup cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Epilim 200mg/5ml Syrup?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Epilim 200mg/5ml Syrup?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Sodium valproate 200mg/5ml
Safety Advice
Pregnancy
Use during pregnancy is generally not recommended unless absolutely necessary.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Limited data available in liver disease patients.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
