Keppra 500mg Tablet

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Keppra 500mg Tablet contains levetiracetam 500mg, an anticonvulsant (anti-epileptic) medicine used, alone or with other anti-epileptic drugs, to control partial-onset seizures, myoclonic seizures, and primary generalised tonic-clonic seizures in people with epilepsy.

Levetiracetam works by binding to a protein on nerve cells called synaptic vesicle protein 2A (SV2A), which helps regulate the release of neurotransmitters. This action is thought to dampen abnormal, excessive electrical activity in the brain that leads to seizures.

How it Works

Levetiracetam binds selectively to SV2A on presynaptic nerve terminals, modulating vesicle release of neurotransmitters and reducing the hypersynchronised neuronal firing that underlies seizure activity, without the sodium- or calcium-channel mechanisms used by many older anti-epileptic drugs.

Directions for Use

Take Keppra 500mg Tablet at evenly spaced times each day, with or without food, exactly as prescribed by your specialist. Swallow the tablet whole with water. Do not stop this medicine suddenly, as abruptly discontinuing an anti-epileptic drug can trigger rebound seizures or, rarely, status epilepticus – any dose change must be made gradually under specialist supervision.

Dosage

Treatment with Keppra 500mg Tablet is started at a low dose and increased gradually by your doctor (a specialist, usually a neurologist) based on seizure control and tolerability, typically given in two divided doses per day. Dosing is individualised and must never be adjusted or stopped without your specialist’s guidance.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Drowsiness or sleepiness
  • Headache
  • Dizziness
  • Irritability or mood changes
  • Loss of appetite
  • Fatigue
  • Nasal congestion

Contraindications

  • Known hypersensitivity to levetiracetam or any ingredient in this product
  • Use only under specialist supervision in significant renal impairment, as the dose must be reduced
  • Use in pregnancy only if the specialist judges the benefit outweighs the risk, with close monitoring

Drug / Food Interactions

  • Alcohol and other CNS depressants (e.g. sedatives, sleeping tablets) may add to drowsiness and impair alertness
  • Other anti-epileptic drugs may be combined under specialist supervision, with monitoring for additive CNS effects
  • Probenecid may reduce the renal clearance of levetiracetam’s main metabolite
  • Methotrexate levels may be affected when combined with levetiracetam

Quick Tips

  • Never stop or change this medicine on your own – seizure control depends on consistent specialist-guided dosing
  • Keep a seizure diary to help your specialist assess how well the medicine is working
  • Avoid driving or operating machinery until you know how this medicine affects you
  • Contact your care team immediately if you notice low mood, unusual thoughts, or behavioural changes

Frequently Asked Questions

What is Keppra 500mg Tablet used for?

Keppra 500mg Tablet is used to control certain types of seizures in epilepsy, either on its own or together with other anti-epileptic medicines, as prescribed by your neurologist or specialist.

Why is specialist follow-up important with this medicine?

Epilepsy treatment needs regular specialist review to check seizure control, adjust the dose safely, and monitor for mood or behavioural side effects – never manage this medicine without ongoing specialist input.

Can I stop this medicine once my seizures are controlled?

No, you should never stop levetiracetam suddenly, even if seizures have stopped, without your specialist’s guidance, as abrupt withdrawal can trigger rebound seizures.

Will this medicine affect my mood?

Some people experience irritability, anxiety, or low mood while taking levetiracetam. Contact your doctor or care team immediately if you notice significant mood changes or thoughts of self-harm.

What should I do if I miss a dose of Keppra 500mg Tablet?

Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose, and contact your specialist if you miss doses frequently.

Can I buy Keppra 500mg Tablet from DoctorOnCall?

Yes, Keppra 500mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Keppra 500mg Tablet according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Keppra 500mg Tablet?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Keppra 500mg Tablet cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Keppra 500mg Tablet?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Keppra 500mg Tablet?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Levetiracetam 500mg

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Generally Safe

Generally safe, but caution may be required in some patients.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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