Keppra 500mg Tablet

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Brand GSK
Manufacturer GSK
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  • FDA Approved
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Keppra 500mg Tablet is a prescription-only medicine (POM) that contains Levetiracetam 500mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Keppra 500mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Keppra 500mg Tablet at evenly spaced times each day, with or without food, exactly as prescribed by your specialist. Swallow the tablet whole with water. Do not stop this medicine suddenly, as abruptly discontinuing an anti-epileptic drug can trigger rebound seizures or, rarely, status epilepticus – any dose change must be made gradually under specialist supervision.

Dosage

Treatment with Keppra 500mg Tablet is started at a low dose and increased gradually by your doctor (a specialist, usually a neurologist) based on seizure control and tolerability, typically given in two divided doses per day. Dosing is individualised and must never be adjusted or stopped without your specialist’s guidance.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Drowsiness or sleepiness
  • Headache
  • Dizziness
  • Irritability or mood changes
  • Loss of appetite
  • Fatigue
  • Nasal congestion

Contraindications

  • Known hypersensitivity to levetiracetam or any ingredient in this product
  • Use only under specialist supervision in significant renal impairment, as the dose must be reduced
  • Use in pregnancy only if the specialist judges the benefit outweighs the risk, with close monitoring

Drug / Food Interactions

  • Alcohol and other CNS depressants (e.g. sedatives, sleeping tablets) may add to drowsiness and impair alertness
  • Other anti-epileptic drugs may be combined under specialist supervision, with monitoring for additive CNS effects
  • Probenecid may reduce the renal clearance of levetiracetam’s main metabolite
  • Methotrexate levels may be affected when combined with levetiracetam

Quick Tips

  • Never stop or change this medicine on your own – seizure control depends on consistent specialist-guided dosing
  • Keep a seizure diary to help your specialist assess how well the medicine is working
  • Avoid driving or operating machinery until you know how this medicine affects you
  • Contact your care team immediately if you notice low mood, unusual thoughts, or behavioural changes

Ingredients / Active Ingredients

  • Levetiracetam 500mg

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Generally Safe

Generally safe, but caution may be required in some patients.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandGSK
ManufacturerGSK
ClassificationPrescription medicine
Ingredients / Active IngredientsLevetiracetam
Pack Size100s, 10s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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