Leprosy

Medical Review

Written by: Dr. Von Chiao Wen Doctor of Medicine (MD), N.I. Pirogov Russian National Research Medical University
Reviewed by: Dr. Lee Chin Meng Doctor of Medicine (MD), Manipal Academy of Higher Education (MAHE)

Overview of Leprosy

Leprosy is a disease caused by infection of Mycobacterium leprae. It is also known as Hansen’s Disease named after the physician that identified the bacteria. Leprosy affects the skin, peripheral nerves, mucosal surfaces of the upper respiratory tract and the eyes. Given early treatment, Leprosy is mostly curable and deflect most disabilities.

Signs and Symptoms of Leprosy

Discolored patches of skin, usually flat, lighter than the skin around, Growths (nodules) on the skin, Thick or dry skin, Painless ulcers on the soles of feet, Painless swelling or lumps on the face or earlobes, Loss of eyebrows or eyelashes, Numbness of affected areas of the skin, Muscle weakness or paralysis, Enlarged nerves, Eye problems that may lead to blindness

Common Causes of Leprosy

Transmitted from infected people by respiratory droplet

Risk Factors of Leprosy

Immunocompromised individual, Living in a country where the disease is widespread e.g.: Ethiopia, Madagascar, Nigeria, Bangladesh, India, Indonesia, Myanmar, Brazil

Investigation Techniques for Leprosy

Cardinal sign of leprosy through physical examination, Slit skin smear/typical histology in a skin biopsy: to find acid fast bacilli

Treatment and Prevention of Leprosy

Stop the infection with chemotherapy: Rifampicin, dapsone, clofazamine, fluoroquinolones, pefloxacin, ofloxacin, clarithromycin, Treat the reactions: prednisolone, Educate patient about leprosy: after 3 days of chemotherapy, they are not infectious, Prevent disability, Support the patient socially and psychologically, BCG vaccination has been shown to give as prevention,

Available Leprosy Medicines

No medicines currently available for this condition.

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