Alkeran 50mg/10ml Injection

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Alkeran 50mg/10ml Injection is a prescription-only medicine (POM) presented as an injection, with Melphalan 50mg/10ml as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

This medicine is prepared and administered only by trained healthcare professionals as an IV infusion in a hospital or specialist infusion setting.

Dosage

Dosing varies greatly by indication – lower doses for standard myeloma regimens versus much higher doses for transplant conditioning – and is calculated and closely monitored by the treating specialist based on body weight or surface area and blood counts.

Shelf Life

Refer to the expiry date printed on the packaging; this medicine is stored and handled only by healthcare facilities.

Storage Instructions

Stored under controlled conditions by the pharmacy or hospital as specified by the manufacturer; not intended for home storage.

Side Effects

  • Nausea and vomiting
  • Fatigue and weakness
  • Loss of appetite
  • Low blood cell counts (increased risk of infection, bleeding)
  • Mouth sores or ulcers
  • Hair thinning or loss
  • Skin rash

Contraindications

  • Known hypersensitivity to melphalan
  • Pregnancy, due to the risk of serious harm to the developing baby
  • Severe, unresolved bone marrow suppression from previous treatment, unless specifically assessed by the specialist team

Drug / Food Interactions

  • Other bone-marrow-suppressing medicines increase the risk of severe low blood counts when combined with melphalan.
  • Live vaccines are generally avoided during and after treatment, as advised by the specialist team.
  • Inform your treating specialist of all medicines and supplements you are taking.

Quick Tips

  • Attend every scheduled blood count check, as this medicine requires close monitoring.
  • Report fever, chills, or signs of infection to your care team immediately, especially in the days following high-dose treatment.
  • Maintain good oral hygiene and report mouth sores promptly, as these are common with this medicine.
  • Stay well hydrated as advised by your care team to support kidney function during treatment.

Frequently Asked Questions

Is Alkeran 50mg/10ml Injection a prescription medicine?

Yes. Alkeran 50mg/10ml Injection is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Alkeran 50mg/10ml Injection contain?

Alkeran 50mg/10ml Injection is supplied as an injection and contains Melphalan 50mg/10ml. The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Alkeran 50mg/10ml Injection is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Alkeran 50mg/10ml Injection?

Take it exactly as written on your prescription label. Do not increase, reduce or skip doses on your own, and do not continue beyond the period your doctor has prescribed. Practical handling steps are set out in the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Alkeran 50mg/10ml Injection?

Stored under controlled conditions by the pharmacy or hospital as specified by the manufacturer; not intended for home storage. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Alkeran 50mg/10ml Injection on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Alkeran 50mg/10ml Injection?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.

Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Alkeran 50mg/10ml Injection be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Alkeran 50mg/10ml Injection registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Melphalan 50mg/10ml

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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