Apo-Trihex 2mg Tablet
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Overview
Apo-Trihex 2mg Tablet contains trihexyphenidyl 2mg, an anticholinergic (antimuscarinic) medicine used to relieve the tremor, muscle stiffness (rigidity), and slowness of movement seen in Parkinson’s disease, and to control drug-induced extrapyramidal symptoms (EPS) caused by certain antipsychotic medicines.
In Parkinson’s disease and drug-induced EPS, there is a relative excess of the chemical messenger acetylcholine compared to dopamine in the parts of the brain that control movement. Trihexyphenidyl works by blocking acetylcholine’s action, helping to restore the balance between these two chemical messengers and reducing tremor and stiffness.
How it Works
Trihexyphenidyl blocks central muscarinic acetylcholine receptors in the basal ganglia, the brain region that coordinates movement. By reducing excessive cholinergic activity relative to dopamine, it helps to lessen tremor, rigidity, and abnormal movements.
Directions for Use
Take Apo-Trihex 2mg Tablet exactly as prescribed, usually with or after food to reduce stomach upset. Swallow the tablet with a glass of water. If you are taking it several times a day, try to space the doses evenly and take them at the same times each day to keep symptom control consistent.
Dosage
Treatment with Apo-Trihex 2mg Tablet usually starts at a low dose, such as 1mg daily, which your doctor will gradually increase over several days to a total daily dose (commonly divided into 3-4 doses) that controls your symptoms with the fewest side effects. The exact dose is individualised based on your response and tolerance, so always follow your doctor’s instructions rather than adjusting the dose yourself.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dry mouth
- Blurred vision
- Dizziness or lightheadedness
- Constipation
- Difficulty urinating
- Nausea
- Nervousness or confusion (especially in elderly patients)
Contraindications
- Known hypersensitivity to trihexyphenidyl
- Narrow-angle (angle-closure) glaucoma
- Myasthenia gravis
- Untreated urinary retention or significant bladder outflow obstruction
- Severe gastrointestinal obstruction or paralytic ileus
Drug / Food Interactions
- Other anticholinergic medicines (e.g. some antihistamines, tricyclic antidepressants) may add to dry mouth, blurred vision, and confusion
- Antipsychotic medicines may have altered effects when combined with trihexyphenidyl
- Alcohol and other central nervous system depressants can worsen drowsiness and dizziness
- Digoxin levels may be affected, requiring monitoring
Quick Tips
- Sip water often or chew sugar-free gum to ease dry mouth
- Take a fibre-rich diet and stay hydrated to reduce constipation
- Be cautious in hot weather, as this medicine can reduce sweating and increase heat sensitivity
- Avoid driving or operating machinery until you know how this medicine affects you
Frequently Asked Questions
What is Apo-Trihex 2mg Tablet used for?
Apo-Trihex 2mg Tablet is used to help control tremor, muscle stiffness, and movement problems in Parkinson’s disease, and to manage muscle stiffness or spasms caused by certain antipsychotic medicines.
Why do I need to increase my dose slowly?
Trihexyphenidyl doses are usually started low and increased gradually so your doctor can find the dose that controls your symptoms while keeping side effects like dry mouth and blurred vision manageable.
Can this medicine cause confusion, especially in older adults?
Yes, older adults can be more sensitive to trihexyphenidyl’s effects on the brain, including confusion or memory problems. Report any new confusion, agitation, or hallucinations to your doctor promptly.
Is it safe to stop this medicine suddenly?
Do not stop this medicine abruptly without your doctor’s advice, as this can cause your Parkinson’s or movement symptoms to worsen. Your doctor will advise on how to adjust or stop treatment if needed.
What should I do if I miss a dose of Apo-Trihex 2mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Apo-Trihex 2mg Tablet from DoctorOnCall?
Yes, Apo-Trihex 2mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Apo-Trihex 2mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Apo-Trihex 2mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Apo-Trihex 2mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Apo-Trihex 2mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Apo-Trihex 2mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Trihexyphenidyl 2mg
Safety Advice
Pregnancy
Limited information is available regarding use during pregnancy. Use only if clearly needed.
Breastfeeding
Use during breastfeeding should only be done if prescribed and monitored by a doctor.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
No data is available regarding the effect of this medicine on driving ability.
Medical Review
