Axcel Bromhexine 4mg/5ml Syrup

Brand Axcel
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Axcel Bromhexine 4mg/5ml Syrup is an oral syrup containing bromhexine hydrochloride 4 mg in every 5 ml, manufactured by Kotra Pharma (M) Sdn Bhd in Malaysia under the Axcel brand. It is a children’s syrup with a fruity flavour, marketed in bottles of 60 ml and 100 ml, so please check the pack size shown on the listing you are ordering. It is intended to be measured with a dosing cup or oral syringe.

Bromhexine is classified as a mucolytic expectorant, meaning it acts on the mucus-producing glands of the airways to change the thickness of the mucus they release. The syrup format allows small, age-based volumes to be measured, which is why the label gives different amounts for babies, young children, older children, and adults. It contains no antibiotic, no codeine or other cough suppressant, and no decongestant.

It is an over-the-counter product listed on DoctorOnCall, but please note that in Singapore bromhexine is regulated as a prescription-only medicine with an exemption allowing supply without prescription in certain circumstances, so our pharmacist team will guide you on suitable use. Please read the label carefully, use the correct volume for the age, and speak to our pharmacist team before ordering if the syrup is for a child under 2 years, or for anyone who is pregnant, breastfeeding, or has a stomach ulcer or liver or kidney problems. Please keep the packaging and dosing device together so the age-based amounts can be checked before every dose.

Directions for Use

For oral administration only, to be taken 3 times a day. Shake the bottle before use and measure the dose with a clean dosing cup or oral syringe, not a household spoon. The amounts are based on age: children under 2 years take 1.25 ml (1 mg); children 2 to 6 years take 2.5 ml (2 mg); children 7 to 12 years take 5 ml (4 mg); adults and children over 12 years take 10 ml (8 mg).

Encourage plenty of fluids during the day. Do not give more than the amount stated for the age, and speak to a doctor or pharmacist before giving the syrup to a baby or a child under 2 years. Close the cap tightly after each use and avoid mixing the syrup with other liquid medicines.

Dosage

Taken 3 times a day. Children under 2 years: 1.25 ml (1 mg). Children 2 to 6 years: 2.5 ml (2 mg). Children 7 to 12 years: 5 ml (4 mg). Adults and children over 12 years: 10 ml (8 mg). Always measure with an accurate dosing device and follow a doctor’s or pharmacist’s advice for a child’s age and weight.

If you miss a dose, give it when you remember unless it is nearly time for the next dose, and never give a double dose. Stop and see a doctor if a rash, blisters, mouth sores, or breathing difficulty develops, or if the cough lasts more than 7 days, worsens, or comes with high fever or noisy breathing.

Storage Instructions

Store in a cool, dry place at the temperature stated on the packaging (usually below 30°C) away from direct sunlight, with the cap tightly closed. Do not freeze the syrup, and keep it out of the sight and reach of children.

Side Effects

  • Nausea
  • Vomiting
  • Abdominal discomfort
  • Diarrhea
  • Skin rash or allergic reactions (rare)
  • Dizziness

Contraindications

  • Known hypersensitivity to bromhexine, ambroxol, or any other ingredient in the syrup.
  • Use in babies and children under 2 years without advice from a doctor or pharmacist.

Drug / Food Interactions

  • Bromhexine may increase the penetration of certain antibiotics, such as erythromycin, cephalexin, and amoxicillin, into lung tissue; check with a doctor or pharmacist before combining.
  • Cough suppressants (antitussives) taken together with bromhexine may cause thinned mucus to build up in the airways because the cough reflex is reduced, so discuss this combination with a pharmacist.
  • Tell your doctor or pharmacist about all other medicines and supplements being taken.
  • No specific food interactions are known; encourage plenty of fluids during use.

Quick Tips

  • Use the dosing cup or an oral syringe and never a household spoon, as the amounts are small and age-specific.
  • Shake the bottle gently before each dose and keep the cap on tightly.
  • Give plenty of water or other fluids through the day.
  • Give the last dose earlier in the evening rather than right at bedtime.
  • Check the age band on the label carefully before giving the syrup to a child.
  • Do not combine with a cough suppressant unless a pharmacist has advised it.

Ingredients / Active Ingredients

  • Active ingredient: Bromhexine hydrochloride 4 mg per 5 ml.
  • Ingredient class: Mucolytic expectorant.
  • Dosage form: Oral syrup with a fruity flavour, marketed in 60 ml and 100 ml bottles.
  • Inactive ingredients: Not fully listed in the sources reviewed, so please check the packaging, especially if a child has a known allergy or sugar-related dietary restriction.

Safety Advice

Pregnancy

Limited Data

Limited information is available regarding use during pregnancy. Use only if clearly needed.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Precautions: Use Axcel Bromhexine 4mg/5ml Syrup with caution if there is a stomach or duodenal ulcer, severe liver or kidney impairment, or asthma, and speak to a doctor or pharmacist before use in these situations. Pregnant and breastfeeding women should seek medical advice first. Always give the volume that matches the age band, and check with a doctor or pharmacist before giving it to a baby or a child under 2 years.

When to See a Doctor or Pharmacist: See a doctor if the person develops a skin rash, blisters, or mouth sores, or difficulty breathing while taking the syrup. Please also seek advice if the cough lasts more than 7 days, brings up blood, is accompanied by high fever or noisy breathing, or if a young child has a persistent cough.

Frequently Asked Questions

Product Specifications

BrandAxcel
ClassificationNon-prescription
Ingredients / Active IngredientsBromhexine
Volume100ml
Shelf LifeUse before the expiry date printed on the bottle and carton. After opening, keep the cap tightly closed and discard the syrup if it changes colour, smell, or consistency, or after the period stated on the label.

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