Biowell Pensic 450mg/35mg Tablet

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Overview

Biowell Pensic 450mg/35mg Tablet is a combination tablet containing paracetamol 450mg, an analgesic and antipyretic, and orphenadrine citrate 35mg, a centrally-acting muscle relaxant. It is used to relieve muscular pain and stiffness, such as backache and muscle spasm, associated with musculoskeletal conditions. This product is manufactured by Biowell, and is the same paracetamol-orphenadrine combination as other brands such as Anarex, made by a different manufacturer.

Paracetamol reduces pain and fever through actions in the central nervous system, while orphenadrine relaxes tense skeletal muscle and has mild anticholinergic properties that can further enhance the overall pain-relieving effect of the combination.

How it Works

Paracetamol is thought to reduce pain and fever mainly through central inhibition of prostaglandin synthesis, while orphenadrine acts on the central nervous system to reduce skeletal muscle tone and spasm, and also has some analgesic and antihistaminic activity that complements paracetamol’s effect.

Directions for Use

Take Biowell Pensic 450mg/35mg Tablet with food to help reduce stomach upset, swallowing the tablet whole with water. Avoid taking any other paracetamol-containing products at the same time to prevent accidental paracetamol overdose.

Dosage

The usual dose of Biowell Pensic 450mg/35mg Tablet is 1-2 tablets up to three times daily as needed, not exceeding the maximum daily dose advised by your doctor or pharmacist. Do not exceed the recommended dose or duration of use.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dry mouth
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Nausea or vomiting
  • Constipation
  • Difficulty urinating
  • Headache

Contraindications

  • Known hypersensitivity to paracetamol or orphenadrine
  • Myasthenia gravis (orphenadrine can worsen muscle weakness)
  • Narrow-angle glaucoma
  • Urinary retention or significant prostate enlargement
  • Severe liver disease

Drug / Food Interactions

  • Other paracetamol-containing products (including many cold/flu remedies) increase the risk of paracetamol overdose and liver damage
  • Alcohol increases the risk of liver toxicity with paracetamol and adds to orphenadrine’s drowsiness
  • Other sedating or anticholinergic medicines increase drowsiness and dry mouth/blurred vision
  • Warfarin’s effect may be enhanced with regular paracetamol use, requiring closer monitoring

Quick Tips

  • Check the labels of other medicines you take to avoid taking more than one paracetamol-containing product at a time
  • Avoid alcohol while taking this medicine
  • Avoid driving or operating machinery until you know how this medicine affects you, as it can cause drowsiness
  • Do not exceed the recommended duration of use without consulting your doctor

Frequently Asked Questions

What is Biowell Pensic 450mg/35mg Tablet used for?

Biowell Pensic 450mg/35mg Tablet is used to relieve muscular pain and stiffness, such as backache and muscle spasm, combining a pain reliever with a muscle relaxant.

Can I take this with other paracetamol-based medicines?

No. Avoid combining this with other paracetamol-containing products, including cold and flu remedies, as this can lead to an accidental paracetamol overdose and serious liver damage.

Will this medicine make me drowsy?

Yes, orphenadrine can cause drowsiness or dizziness in some people. Avoid driving or operating machinery until you know how this medicine affects you, and avoid alcohol.

How long can I take this medicine for?

This medicine is generally intended for short-term relief of muscle pain. If your symptoms persist beyond the duration advised by your doctor, seek medical review rather than continuing on your own.

What should I do if I miss a dose of Biowell Pensic 450mg/35mg Tablet?

Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.

Can I buy Biowell Pensic 450mg/35mg Tablet from DoctorOnCall?

Yes, Biowell Pensic 450mg/35mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Biowell Pensic 450mg/35mg Tablet according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Biowell Pensic 450mg/35mg Tablet?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Biowell Pensic 450mg/35mg Tablet cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Biowell Pensic 450mg/35mg Tablet?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Biowell Pensic 450mg/35mg Tablet?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Paracetamol 450mg
  • Orphenadrine citrate 35mg

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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