Brexin 20mg Tablet

Brand Chiesi
Manufacturer Chiesi
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Brexin 20mg Tablet is supplied as a tablet, with Piroxicam Beta-cyclodextrin 20mg (equivalent to Piroxicam). It is supplied in pack sizes of 10s and 20s.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Brexin 20mg Tablet should only be taken exactly as prescribed by your doctor, typically once daily, swallowed whole with a full glass of water, preferably with or after food to reduce stomach upset. Do not increase the dose or take it for longer than prescribed, as piroxicam is associated with increased risk of serious gastrointestinal complications with prolonged use.

Dosage

The usual prescribed dose is one 20mg tablet once daily; some patients may be prescribed a lower dose depending on their condition, age, and other risk factors. Your doctor will determine the lowest effective dose for the shortest duration necessary and may review your treatment periodically. Do not adjust your dose without medical advice.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep the tablets in their original packaging until ready for use, and keep out of reach of children.

Side Effects

  • Upset stomach or indigestion
  • Headache or dizziness
  • Diarrhea or constipation
  • Swelling in hands or feet
  • Skin rash or itching
  • Increased blood pressure
  • Heartburn or nausea

Contraindications

  • Known hypersensitivity to piroxicam, other NSAIDs, or aspirin
  • Active or history of peptic ulcer disease or gastrointestinal bleeding
  • Severe heart failure, active cardiovascular disease, or recent heart surgery
  • Severe renal or hepatic impairment
  • Third trimester of pregnancy
  • History of asthma, urticaria, or allergic reactions triggered by NSAIDs

Drug / Food Interactions

  • Other NSAIDs or aspirin — increased risk of gastrointestinal bleeding
  • Anticoagulants such as warfarin — increased bleeding risk
  • ACE inhibitors or angiotensin receptor blockers — reduced antihypertensive effect and risk of kidney impairment
  • Diuretics — reduced effectiveness and increased risk of kidney problems
  • Lithium or methotrexate — increased blood levels and toxicity risk
  • Corticosteroids — increased risk of gastrointestinal ulceration

Quick Tips

  • Only take Brexin 20mg Tablet if prescribed by your doctor following an online consultation
  • Take with food to reduce the chance of stomach irritation
  • Do not exceed the prescribed dose or duration
  • Report any signs of stomach pain, black stools, or unusual bruising to your doctor immediately
  • Attend follow-up reviews as advised, especially with long-term use
  • Avoid alcohol, which can increase the risk of stomach irritation

Ingredients / Active Ingredients

  • Piroxicam Beta-cyclodextrin 20mg (equivalent to Piroxicam)
  • Microcrystalline cellulose
  • Lactose
  • Magnesium stearate
  • Colloidal silicon dioxide

Safety Advice

Pregnancy

Not Advisable

Use during pregnancy is generally not recommended unless absolutely necessary.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

As a long-acting NSAID, piroxicam is generally reserved for chronic conditions requiring sustained anti-inflammatory control and is usually not a first-line choice given its comparatively higher risk of gastrointestinal and skin-related adverse effects. Patients on long-term therapy should be monitored periodically by their doctor for kidney function, blood pressure, and gastrointestinal symptoms. Older adults and those with pre-existing cardiovascular or renal conditions require closer monitoring.

Frequently Asked Questions

Product Specifications

BrandChiesi
ManufacturerChiesi
ClassificationNon-prescription
Ingredients / Active IngredientsPiroxicam
Pack Size10s, 20s
Shelf LifeBrexin 20mg Tablet is typically stable for up to 36 months from the date of manufacture when unopened and stored correctly. Always check the expiry date printed on the packaging and do not use the product past this date.

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Important Medical Information

💊 Recommended Dosage:

The usual prescribed dose is one 20mg tablet once daily; some patients may be prescribed a lower dose depending on their condition, age, and other risk factors. Your doctor will determine the lowest effective dose for the shortest duration necessary and may review your treatment periodically. Do not adjust your dose without medical advice.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to piroxicam, other NSAIDs, or aspirin
  • Active or history of peptic ulcer disease or gastrointestinal bleeding
  • Severe heart failure, active cardiovascular disease, or recent heart surgery
  • Severe renal or hepatic impairment
  • Third trimester of pregnancy
  • History of asthma, urticaria, or allergic reactions triggered by NSAIDs
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Upset stomach or indigestion
  • Headache or dizziness
  • Diarrhea or constipation
  • Swelling in hands or feet
  • Skin rash or itching
  • Increased blood pressure
  • Heartburn or nausea
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.