Breztri Aerosphere Inhalation Aerosol

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Manufacturer Breztri
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Prescription Required

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Breztri Aerosphere Inhalation Aerosol is a prescription-only medicine (POM) presented as a medicine, with Budesonide, Glycopyrrolate and Formoterol fumarate as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Shake the inhaler well before each use. Rinse your mouth with water and spit it out after each use to reduce the risk of oral thrush from the inhaled corticosteroid component. This inhaler is for maintenance use only and is not intended to relieve sudden breathlessness.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children; do not puncture or expose the canister to heat.

Side Effects

  • Throat irritation
  • Hoarseness or voice changes
  • Headache
  • Nausea
  • Cough
  • Oral thrush (fungal infection in the mouth)
  • Increased heart rate
  • Dizziness

Contraindications

  • Known hypersensitivity to budesonide, glycopyrrolate, formoterol, or any ingredient in the formulation
  • Use as a rescue inhaler for acute breathlessness – it is not fast-acting enough for this purpose
  • Uncontrolled narrow-angle glaucoma or significant urinary retention, due to the glycopyrrolate component – requires specialist assessment

Drug / Food Interactions

  • Other medicines from the same classes (other long-acting antimuscarinics or beta agonists) are generally not combined with this inhaler due to overlapping effects.
  • Beta-blockers can reduce the effectiveness of the formoterol component.
  • Medicines that prolong the QT interval should be used cautiously alongside this inhaler.
  • Inform your doctor of all medicines you are taking.

Quick Tips

  • Always rinse your mouth with water and spit it out after using this inhaler to reduce the risk of oral thrush.
  • Use this inhaler regularly as maintenance treatment, not as a rescue inhaler for sudden breathlessness – keep a fast-acting reliever inhaler as directed by your doctor for that purpose.
  • Have your inhaler technique checked periodically by your doctor or pharmacist to ensure you are getting the full dose.
  • Report palpitations, chest discomfort, or worsening breathlessness to your doctor.

Ingredients / Active Ingredients

  • Budesonide
  • Glycopyrrolate
  • Formoterol fumarate

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Safe If Prescribed

Use during breastfeeding should only be done if prescribed and monitored by a doctor.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandAstraZeneca
ManufacturerBreztri
ClassificationPrescription medicine
Ingredients / Active IngredientsFormoterol + Budesonide
Form120 doses
DosageThe usual dose is two inhalations twice daily (morning and evening), but the exact regimen is confirmed by the treating doctor based on the patient’s COPD severity and inhaler technique.
Shelf LifeRefer to the expiry date printed on the packaging.

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