Burinex 1mg Tablet
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Prescription Required
Overview
Burinex 1mg Tablet contains bumetanide 1mg, a potent loop diuretic (a “water tablet”) used to treat fluid retention (oedema) caused by conditions such as heart failure, kidney disease, or liver disease. Burinex is the original branded formulation of bumetanide, developed by Leo Pharma.
Bumetanide works in the kidneys by blocking the reabsorption of sodium, chloride, and water in a specific part of the nephron, causing the body to excrete more urine. This reduces excess fluid in the body, easing swelling and reducing the workload on the heart.
How it Works
Bumetanide inhibits the sodium-potassium-chloride (Na-K-2Cl) co-transporter in the thick ascending limb of the loop of Henle in the kidney, preventing reabsorption of these electrolytes and the water that follows them. This produces a strong, relatively fast diuretic effect that reduces fluid overload in conditions such as heart failure and kidney or liver disease.
Directions for Use
Take Burinex 1mg Tablet in the morning to avoid the need to urinate frequently during the night, with or without food. Swallow the tablet whole with a glass of water. Your doctor may ask you to monitor your body weight and attend regular blood tests to check your electrolyte levels and kidney function.
Dosage
The usual starting dose of Burinex 1mg Tablet is 0.5-1mg once daily, taken in the morning, with your doctor adjusting the dose based on your response and the severity of fluid retention. Higher or divided doses may be used for more severe cases under close medical supervision.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Increased urination
- Dizziness or light-headedness
- Headache
- Low potassium levels (hypokalemia)
- Muscle cramps
- Dehydration
- Nausea
Contraindications
- Known hypersensitivity to bumetanide or, in some cases, to sulfonamide-derived medicines
- Anuria (inability to produce urine)
- Severe electrolyte depletion that has not been corrected
- Hepatic coma or pre-coma associated with severe liver disease
Drug / Food Interactions
- Other blood pressure medicines may have an additive blood-pressure-lowering effect
- Digoxin toxicity risk may increase if bumetanide causes low potassium levels
- Lithium excretion may be reduced, increasing lithium blood levels and the risk of toxicity
- NSAIDs (e.g. ibuprofen) may reduce the diuretic effect of bumetanide
- Aminoglycoside antibiotics may increase the risk of hearing-related side effects when combined
Quick Tips
- Take this medicine in the morning to avoid night-time urination
- Attend scheduled blood tests to monitor your electrolytes and kidney function
- Weigh yourself regularly as advised by your doctor to track fluid changes
- Rise slowly from sitting or lying down to reduce dizziness
Frequently Asked Questions
What is Burinex 1mg Tablet used for?
Burinex 1mg Tablet is used to treat fluid retention (oedema) caused by conditions such as heart failure, kidney disease, or liver disease, helping the body eliminate excess fluid through increased urination.
Why should I take this medicine in the morning?
Taking bumetanide in the morning helps ensure that the increased urination it causes happens mostly during the day, reducing the need to wake up at night to urinate.
Will I need regular blood tests while taking this medicine?
Yes, your doctor will schedule periodic blood tests to monitor your electrolyte levels (such as potassium and sodium) and kidney function, as diuretics can affect these values.
Can this medicine affect my hearing?
Loop diuretics like bumetanide have been associated with hearing changes in rare cases, particularly at high doses or when combined with certain other medicines – report any hearing changes to your doctor.
What should I do if I miss a dose of Burinex 1mg Tablet?
Take the missed dose as soon as you remember, unless it is late in the day – in that case, skip it to avoid night-time urination and continue your regular schedule the next morning. Do not double the dose.
Can I buy Burinex 1mg Tablet from DoctorOnCall?
Yes, Burinex 1mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Burinex 1mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Burinex 1mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Burinex 1mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Burinex 1mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Burinex 1mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Bumetanide 1mg
Safety Advice
Pregnancy
This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
No adequate data available. Consult a doctor before use.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
Medical Review
