Captohexal 25mg Tablet
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Overview
Captohexal 25mg Tablet contains captopril 25mg, an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure (hypertension) and chronic heart failure, and to help protect the kidneys in some patients with diabetic kidney disease.
Captopril works by blocking the enzyme that converts angiotensin I into angiotensin II, a hormone that narrows blood vessels and stimulates aldosterone release. By reducing angiotensin II formation, captopril allows blood vessels to relax and widen, lowering blood pressure and reducing the workload on the heart.
How it Works
Captopril inhibits ACE, preventing the conversion of angiotensin I to angiotensin II and reducing the breakdown of bradykinin, a vasodilating substance. The resulting fall in angiotensin II lowers vascular resistance and aldosterone-driven sodium and water retention, which together lower blood pressure and reduce cardiac workload.
Directions for Use
Take Captohexal 25mg Tablet on an empty stomach, about one hour before meals, as food can reduce how well captopril is absorbed. Swallow the tablet with a glass of water, at the same times each day. Do not stop taking this medicine suddenly without consulting your doctor, even if you feel well.
Dosage
The usual starting dose of Captohexal 25mg Tablet for hypertension is 25mg two to three times daily, which your doctor may adjust up to a higher total daily dose depending on your blood pressure response. Dosing for heart failure is individualised and usually started at a lower dose with gradual titration. Always take exactly as prescribed.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dizziness or lightheadedness, especially after standing up
- Dry cough
- Fatigue or weakness
- Headache
- Changes in taste (metallic or loss of taste)
- Skin rash
- Increased potassium levels in the blood
- Kidney function changes
Contraindications
- Known hypersensitivity to captopril, other ACE inhibitors, or any ingredient in this product
- History of angioedema related to previous ACE inhibitor use
- Pregnancy (can cause serious harm to the developing baby)
- Bilateral renal artery stenosis (narrowing of the arteries supplying both kidneys)
- Concomitant use with aliskiren in patients with diabetes or kidney impairment
Drug / Food Interactions
- Potassium supplements or potassium-sparing diuretics may increase the risk of high blood potassium
- NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
- Lithium levels may increase when combined with captopril
- Other blood pressure medicines may increase the risk of low blood pressure
Quick Tips
- Take on an empty stomach, about an hour before meals, for the best absorption
- Rise slowly from sitting or lying down to reduce dizziness, especially after the first few doses
- Report any persistent dry cough to your doctor, as it is a known effect that may require a medicine change
- Seek immediate medical help if you notice swelling of the face, lips, or tongue
Frequently Asked Questions
What is Captohexal 25mg Tablet used for?
Captohexal 25mg Tablet is used to treat high blood pressure and chronic heart failure, and may also be used to help protect kidney function in certain patients with diabetes.
Why do I have a dry cough since starting this medicine?
A persistent dry cough is a well-known effect of ACE inhibitors like captopril, thought to be related to increased bradykinin levels. Tell your doctor if the cough is bothersome, as an alternative medicine may be considered.
Why should I take Captohexal 25mg Tablet before meals?
Food can reduce the absorption of captopril, so it is generally recommended to take it about an hour before meals for more consistent effect.
Can I take this medicine if I am pregnant?
No, captopril should not be used during pregnancy as it can seriously harm the developing baby. Speak to your doctor immediately if you are pregnant, think you may be pregnant, or are planning pregnancy.
What should I do if I miss a dose of Captohexal 25mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Captohexal 25mg Tablet from DoctorOnCall?
Yes, Captohexal 25mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Captohexal 25mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Captohexal 25mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Captohexal 25mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Captohexal 25mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Captohexal 25mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Captopril 25mg
Safety Advice
Pregnancy
Use during pregnancy is generally not recommended unless absolutely necessary.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
