Combiwave SF 125 Pressured Inhalation

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Manufacturer Glenmark
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Combiwave SF 125 Pressured Inhalation contains Salmeterol 25mcg (as salmeterol xinafoate) per actuation and Fluticasone propionate 125mcg per actuation and is available as a medicine. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Combiwave SF 125 Pressured Inhalation are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Shake Combiwave SF 125 Pressured Inhalation well before each use, breathe out fully, then form a tight seal around the mouthpiece and breathe in slowly and deeply while pressing down on the canister, holding your breath for about 10 seconds before breathing out. Rinse your mouth with water and spit it out after each use to reduce the risk of oral thrush and hoarseness, and use a spacer device if your doctor recommends one.

Dosage

The usual dose of Combiwave SF 125 Pressured Inhalation is 2 inhalations twice daily, morning and evening, though your doctor will determine the exact strength and number of inhalations based on the severity of your asthma or COPD. This inhaler is for regular, scheduled use only and must not be used for sudden breathlessness.

Storage Instructions

Store below 30°C, away from direct sunlight and out of reach of children. Do not puncture, break, or burn the canister even when it appears empty, and avoid exposing it to temperatures above 50°C, as the canister is pressurised.

Side Effects

  • Headache
  • Sore throat
  • Hoarseness or voice changes
  • Cough
  • Nausea
  • Fungal infection in the mouth (oral thrush)
  • Mild muscle or bone pain

Contraindications

  • Known hypersensitivity to salmeterol, fluticasone propionate, or any ingredient in this product
  • Not for use as a reliever during an acute asthma attack or sudden worsening of symptoms
  • Use with caution in patients with pulmonary tuberculosis or severe untreated respiratory infections

Drug / Food Interactions

  • Strong CYP3A4 inhibitors (e.g. ketoconazole, ritonavir) can significantly increase fluticasone’s systemic absorption and side effects
  • Beta-blockers (including some eye drops) may reduce salmeterol’s bronchodilating effect and should generally be avoided
  • Other sympathomimetic medicines increase the risk of tremor and cardiovascular side effects
  • Diuretics (e.g. furosemide) may worsen low blood potassium levels when combined with salmeterol

Quick Tips

  • Use this inhaler regularly as prescribed, even when you feel well, as it is a preventer/maintenance treatment
  • Always carry a separate fast-acting reliever inhaler for sudden symptoms
  • Rinse your mouth with water after every use to prevent oral thrush and hoarseness
  • Check the dose counter (if fitted) and replace the inhaler before it runs out

Ingredients / Active Ingredients

  • Salmeterol 25mcg (as salmeterol xinafoate) per actuation
  • Fluticasone propionate 125mcg per actuation

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Frequently Asked Questions

Product Specifications

BrandGlenmark
ManufacturerGlenmark
ClassificationPrescription medicine
Ingredients / Active IngredientsSalmeterol + Fluticasone
Form150 doses
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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