Crinone 8% Vaginal Gel

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Crinone 8% Vaginal Gel contains natural progesterone 8% (90mg per applicator dose) in a bioadhesive vaginal gel, used to provide progesterone supplementation for luteal phase support in assisted reproductive technology (such as IVF) and for the treatment of secondary amenorrhoea.

The bioadhesive gel adheres to the vaginal wall and releases progesterone steadily, supporting transformation of the uterine lining into a state suitable for embryo implantation and helping maintain early pregnancy by reducing uterine contractility.

How it Works

Progesterone released from the bioadhesive gel is absorbed directly through the vaginal wall, achieving locally high uterine tissue levels while largely avoiding first-pass liver metabolism. This supports consistent endometrial transformation and helps sustain early pregnancy when progesterone from the ovary or placenta needs supplementation.

Directions for Use

Wash your hands before use, then insert the pre-filled applicator of Crinone 8% Vaginal Gel into the vagina as instructed by your doctor, ideally at a consistent time each day. Some gel residue after use is expected, as the bioadhesive formulation is designed to remain in contact with the vaginal wall, so this does not mean the dose was not absorbed properly.

Dosage

The usual dose of Crinone 8% Vaginal Gel is one applicator (90mg) inserted vaginally once daily, though your fertility specialist may prescribe twice-daily dosing depending on your specific assisted reproduction protocol. Treatment is often continued through the early weeks of pregnancy if conception occurs, as directed by your doctor.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache or dizziness
  • Breast tenderness
  • Mood swings or irritability
  • Bloating or stomach discomfort
  • Sleep disturbances
  • Nausea
  • Fatigue

Contraindications

  • Undiagnosed vaginal bleeding
  • Known or suspected breast or genital tract malignancy
  • Active thromboembolic disorder (blood clot) or a strong history of clotting problems
  • Missed or incomplete abortion
  • Severe liver impairment

Drug / Food Interactions

  • Other hormonal medicines should only be combined under medical supervision
  • Other vaginal products used at the same time may affect gel adherence and absorption – ask your doctor before combining products
  • Inform your doctor of all other medicines and supplements you are taking, particularly other progestogens

Quick Tips

  • Do not be alarmed by gel residue after application – this is normal for this bioadhesive formulation
  • Try to use it at the same time each day to maintain consistent progesterone levels
  • Avoid interrupting this treatment without medical advice, especially in early pregnancy
  • Store and handle applicators as described on the product packaging

Frequently Asked Questions

Why do I notice gel residue after using Crinone 8% Vaginal Gel?

This is expected and normal – the bioadhesive gel is designed to stay in contact with the vaginal wall to release progesterone steadily, and residue does not mean the dose failed to absorb.

Can I use Crinone 8% Vaginal Gel at any time of day?

It is best to use it at a similar time each day as advised by your doctor, to help maintain steady progesterone levels, particularly during fertility treatment cycles.

Do I continue this medicine if I become pregnant?

In many assisted reproduction protocols, progesterone support is continued through the early weeks of pregnancy as directed by your fertility specialist – do not stop without medical advice.

Is Crinone 8% Vaginal Gel the same as a progesterone pessary?

Both provide vaginal progesterone, but this product is a bioadhesive gel delivered by a pre-filled applicator rather than a solid pessary; your doctor will advise which is appropriate for your specific treatment.

What should I do if I miss a dose of Crinone 8% Vaginal Gel?

Use the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip it and continue your regular schedule. Contact your doctor if you are unsure.

Can I buy Crinone 8% Vaginal Gel from DoctorOnCall?

Yes, Crinone 8% Vaginal Gel is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Crinone 8% Vaginal Gel according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Crinone 8% Vaginal Gel?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Crinone 8% Vaginal Gel cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Crinone 8% Vaginal Gel?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Crinone 8% Vaginal Gel?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Progesterone 8% (90mg per applicator dose)

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Limited Data

Limited data in kidney disease patients. Use only if necessary.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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