Cyclogest 400mg Pessary

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Cyclogest 400mg Pessary contains micronised natural progesterone 400mg as a pessary for vaginal or rectal insertion, used to support the luteal phase in assisted reproduction (such as IVF), and to treat conditions such as premenstrual syndrome, secondary amenorrhoea, and threatened or recurrent miscarriage under specialist advice.

Progesterone helps prepare and maintain the uterine lining (endometrium) in a form suitable for implantation and early pregnancy, and reduces uterine muscle contractility, replacing or supplementing the progesterone your body would normally produce during this phase of the cycle or in early pregnancy.

How it Works

Progesterone released from the pessary is absorbed through the vaginal or rectal mucosa, supporting transformation of the endometrium into a secretory, implantation-ready state and suppressing uterine contractions. This mimics and supplements the natural progesterone produced by the ovary after ovulation and by the placenta in early pregnancy.

Directions for Use

Wash your hands before and after use, and insert the Cyclogest 400mg Pessary pessary high into the vagina or rectum as instructed by your doctor. Inserting it while lying down can improve comfort and reduce leakage; if vaginal irritation or discharge becomes bothersome, ask your doctor whether the rectal route may be more suitable for you.

Dosage

The dose of Cyclogest 400mg Pessary is individualised by your doctor, typically ranging from one pessary twice daily to up to three times daily depending on your specific treatment protocol, such as fertility treatment support or luteal phase deficiency. Follow your doctor’s specific instructions on dose, route, and duration closely.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache or dizziness
  • Breast tenderness
  • Mood swings or irritability
  • Bloating or stomach discomfort
  • Sleep disturbances
  • Nausea
  • Fatigue

Contraindications

  • Undiagnosed vaginal bleeding
  • Known or suspected breast or genital tract malignancy
  • Active thromboembolic disorder (blood clot) or a strong history of clotting problems
  • Missed or incomplete abortion
  • Severe liver disease

Drug / Food Interactions

  • Other hormonal medicines should only be combined under medical supervision, as effects on the reproductive hormone balance can overlap
  • Strong CYP3A4 enzyme inducers or inhibitors could theoretically alter progesterone levels, though vaginal/rectal absorption largely bypasses liver first-pass metabolism
  • Inform your doctor of all other medicines and supplements you are taking, particularly other progestogens

Quick Tips

  • Insert at bedtime if you notice drowsiness, as this can reduce daytime sleepiness
  • Use a panty liner to manage any oily residue or discharge between doses
  • Do not stop this medicine abruptly in early pregnancy without your doctor’s advice
  • Keep all scheduled follow-up appointments so your doctor can monitor your response to treatment

Frequently Asked Questions

Should I insert Cyclogest 400mg Pessary vaginally or rectally?

Your doctor will advise which route is appropriate for your specific treatment; some people are advised to switch to the rectal route if vaginal irritation or discharge becomes bothersome.

Will Cyclogest 400mg Pessary make me feel drowsy?

Yes, some absorbed progesterone can cause mild drowsiness or dizziness, so many people find it more comfortable to insert their dose at bedtime.

Is it normal to notice some discharge or residue after using this pessary?

Yes, mild vaginal discharge or residue is common with vaginally inserted progesterone pessaries and is not usually a cause for concern, but let your doctor know if it becomes heavy, irritating, or foul-smelling.

Can I stop using Cyclogest 400mg Pessary once I get a positive pregnancy test?

No, do not stop without your doctor’s advice – in many fertility treatment protocols, progesterone support continues through the early weeks of pregnancy to help maintain the pregnancy.

What should I do if I miss a dose of Cyclogest 400mg Pessary?

Insert the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Contact your doctor if you are unsure.

Can I buy Cyclogest 400mg Pessary from DoctorOnCall?

Yes, Cyclogest 400mg Pessary is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Cyclogest 400mg Pessary according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Cyclogest 400mg Pessary?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Cyclogest 400mg Pessary cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Cyclogest 400mg Pessary?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Cyclogest 400mg Pessary?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Progesterone 400mg

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Limited Data

Limited data in kidney disease patients. Use only if necessary.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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