Installment Available Differin (Adapalene) 0.1% Gel
RxTopical retinoid gel containing adapalene 0.1%. Supplied only against a valid prescription.
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- 0% InterestNo interest on eligible instalments
- Flexible paymentsSpread your payment across monthly instalments
- No hidden feesClear and transparent pricing
Prescription Required
Currently Out of Stock No Longer Available
Prescription required. Once back in stock, a doctor will review your prescription after payment.
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Key Information
What is Differin (Adapalene) 0.1% Gel?
- Differin (Adapalene) 0.1% Gel is a prescription-only medicine (POM) supplied as a gel, containing the active ingredient adapalene 0.1%.
- Adapalene belongs to the class of medicines known as retinoids, and the gel is supplied in a 30g tube.
- In Malaysia, it is available only with a valid prescription from a registered doctor.
- It is for use on the skin only and should be used under medical supervision.
Is this strength right for me?
- Differin is available as a 0.1% gel only. Your doctor will confirm whether it suits you, based on your skin, health, other medicines and individual response.
- Apply a thin layer to clean, dry skin once daily, preferably in the evening, or as your doctor directs.
- Do not use more than prescribed. Applying more does not improve results and may increase irritation.
- Differin gel may not be safe to use during pregnancy, so tell your doctor if you are pregnant or planning a pregnancy.
Delivery, packaging and ordering
- Choose your product and complete an online consultation. Your request is reviewed by a licensed doctor, and approved medication is dispensed by a registered pharmacist before delivery.
- Orders placed outside consultation hours may be queued for review on the next working day.
- The product page lists fast delivery. Check the page for current delivery options and charges.
- Each pack carries its MAL registration number from the Ministry of Health Malaysia, which you can verify through the relevant Ministry of Health resources.
Side effects, safety and when to seek help
- As with any medicine, Differin may cause side effects in some people. Common effects of this type of product include dryness, redness, peeling and a stinging or burning feeling on the skin.
- Do not use it if you are allergic to adapalene or any ingredient in the product. It is also not suitable on broken, sunburned, eczematous or severely irritated skin, as this may worsen irritation.
- Avoid products that contain alcohol, astringents or other drying agents, as these may increase skin irritation. Protect treated skin from strong sun and use sunscreen. Tell your doctor about all medicines and skin products you use.
- Stop using it and contact your doctor if you develop severe irritation, swelling, blistering, or signs of infection. Seek immediate medical attention for swelling of the face or lips, difficulty breathing, or any severe or unexpected reaction.
How to use your Differin (Adapalene) 0.1% Gel
Confirm with your doctor that Differin is suitable for you. Tell them about any allergies, skin conditions, whether you are pregnant, and any other skin products you use.
Wash the area with a gentle cleanser and dry it completely before applying, as damp skin can increase irritation.
Apply a thin, pea-sized layer to the whole area to be treated, usually once daily in the evening, on clean, dry skin, not only on individual spots. Avoid your eyes, lips, nostrils and broken skin, and wash your hands afterwards.
Avoid alcohol-based, astringent or other drying products on the same area. Use sunscreen during the day. Do not stop on your own, and speak to your doctor if irritation is severe or does not settle.
Delivery & Returns
- Malaysia-wide delivery
- No prescription needed
- Licensed pharmacy
- Doctor consultation
If your order arrives damaged
- Do not use Differin Gel if the packaging is damaged, the tube is leaking or torn, or the seal appears to have been tampered with.
- Check the tube and carton carefully before use.
- Contact us on WhatsApp immediately and provide photos of the outer packaging and the tube.
- We’ll review the issue and arrange a replacement at no extra cost if the delivery issue is verified.
Returns policy
As a prescription medicine, Differin (Adapalene) 0.1% Gel cannot be returned or exchanged once it has left our pharmacy, except in cases involving a verified delivery issue, such as damaged packaging, an incorrect item or a missing item.
If there is a problem with your order, contact us within 24 hours of delivery so we can review the issue and advise you on the next steps.
Dosage
Apply a thin, pea-sized amount of Differin (Adapalene) 0.1% Gel once daily, usually in the evening, to the entire affected area of clean, dry skin – not just individual spots. Your doctor or pharmacist will advise how long to continue treatment, as visible improvement typically takes 4-12 weeks of regular use.
Storage Instructions
Do
- Store in a cool, dry place, following the instructions on the product packaging.
- Keep the cap tightly closed after each use.
- Keep out of reach of children.
- Check the expiry date printed on the tube before use.
Don't
- Don’t leave it in a hot car, bathroom or near a stove.
- Don’t use it after the expiry date.
- Don’t share your medicine with others. It is prescribed for you.
- Don’t use it if the gel changes colour or texture, or the tube is damaged.
Side Effects
Differin Adapalene Gel may cause skin reactions, particularly during the first few weeks of treatment. Symptoms can vary between individuals and may improve as the skin adjusts. Follow your prescriber’s instructions and monitor your skin for persistent or severe reactions.
The skin may become dry, red or flaky, especially during the first few weeks of treatment.
A brief stinging or burning sensation may occur shortly after applying the gel.
Acne may appear temporarily worse during the early stages of treatment. Persistent or severe worsening should be assessed by a healthcare professional.
Your skin may become more sensitive to sunlight. Limit sun exposure, wear protective clothing and use sunscreen as advised.
Important Safety Warning
Stop applying the gel and seek medical advice if you experience severe skin irritation, blistering or other significant skin reactions.
Signs of a serious allergic reaction may include a widespread rash, swelling of the face, lips or tongue, or difficulty breathing. Seek emergency medical attention immediately if these symptoms occur.
This information does not replace the product leaflet or advice from your healthcare professional. As Differin Adapalene Gel is a prescription item, follow your prescriber’s instructions and seek advice if reactions persist, worsen or cause concern.
Contraindications
- Known hypersensitivity to adapalene or any ingredient in this product
- Application to eczematous, sunburnt, or broken skin
- Pregnancy and breastfeeding, unless specifically advised by your doctor
- Concurrent use with other strong topical exfoliants or peeling agents without medical advice
Drug / Food Interactions
- Other topical retinoids, benzoyl peroxide at high strength, or salicylic acid products may increase skin irritation if used together without spacing them out
- Medicated soaps, astringents, or alcohol-based cosmetics can worsen dryness and irritation
- Waxing should be avoided on skin currently being treated, as it can tear irritated skin
- Prolonged sun exposure or sunbed use increases the risk of sunburn on treated skin
Quick Tips
- Start with a small pea-sized amount to gauge how your skin reacts
- Use a fragrance-free, non-comedogenic moisturiser to manage dryness
- Always apply sunscreen during the day while using this product
- Be patient – visible acne improvement usually takes several weeks of consistent use
Ingredients / Active Ingredients
Safety Advice
Pregnancy
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Generally safe, but caution may be required in some patients.
Liver
Generally safe, but caution may be required in some patients.
Alcohol
Consuming alcohol with this medicine is generally safe, but moderate intake is advised.
Driving
This medicine is generally safe and should not impair your driving ability.
How to buy
Go to the DoctorOnCall website
Visit the DoctorOnCall website, then choose or search for Differin (Adapalene) and add it to your cart. Review your cart, enter your information and delivery details, complete your payment securely.
Doctor consultation
A registered doctor reviews your health information, medical history and current medicines through an online consultation before deciding whether Differin is appropriate for you.
Pharmacist dispenses
Once your doctor approves the prescription, a registered pharmacist reviews your order and prepares your medication in accordance with professional pharmacy standards.
Delivery to your door
Your order is packed securely and delivered to your address, with fast delivery options available.
Frequently Asked Questions
Yes. Differin (Adapalene) 0.1% Gel is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
Differin (Adapalene) 0.1% Gel is supplied as a gel and contains Adapalene 0.1%. The full composition is listed in the Composition section on this page and on the product packaging.
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Product Specifications
| Brand | Differin |
|---|---|
| Manufacturer | Galderma |
| Classification | Prescription-only medicine (POM) |
| Ingredients / Active Ingredients | Adapalene |
| Weight | 30g |
| Shelf Life | Refer to the expiry date printed on the product packaging. Do not use the medicine after its expiry date. |
| Ingredients / Active Ingredients | Adapalene |
| Strength | 0.1% |
| Pack Size | 30g tube |
| Dosage | Apply a thin layer to clean, dry skin once daily, preferably in the evening. Follow the instructions of your doctor or pharmacist. |
| Ingredients | Adapalene 0.1%, a retinoid |
| Registration holder | Galderma Malaysia Sdn. Bhd. |
| Form | Gel |
| Frequency | Usually once daily, preferably in the evening. Follow your doctor’s or pharmacist’s instructions. |
| Per Dose | A thin, pea-sized layer over the affected area |
| Storage | Store according to the instructions on the product packaging. Keep in a cool, dry place away from direct sunlight and excessive heat. Keep out of reach of children. |
| Excipients | Refer to the product packaging or leaflet |
Have questions before you buy?
- Which mg is right for me?
- How do I store it?
- What are the sideeffects?
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