Difflam Hextra 2.4mg Sore Throat Lozenges

Brand Difflam
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Overview

Difflam Hextra 2.4mg Sore Throat Lozenges is an Over-the-Counter (OTC) oral lozenge product containing benzydamine hydrochloride 2.4mg as its active ingredient. It is sold through DoctorOnCall, a licensed online pharmacy serving customers in Malaysia and Singapore, and is presented as a sugar-free, slow-dissolving lozenge.

Benzydamine hydrochloride belongs to a class of topical oral agents used in lozenge form, and this product is formulated with isomalt and aspartame as sweetening agents rather than sugar, together with citric acid and flavouring agents. Each lozenge is designed to dissolve gradually in the mouth rather than being chewed or swallowed whole.

Difflam Hextra lozenges are supplied in packs of 12, and the sugar-free formulation distinguishes this product from standard sugar-based throat lozenges on the market, making the dosage form a consideration for people managing their sugar intake, such as those with diabetes.

Directions for Use

  • Allow one lozenge to dissolve slowly in the mouth; do not chew or swallow it whole.
  • Adults and children aged 6 years and above may take one lozenge every 3 hours as needed.
  • Do not take more than 12 lozenges in any 24-hour period.
  • Do not use for longer than 7 consecutive days without checking with a doctor or pharmacist.

Dosage

Adults and children aged 6 years and above: 1 lozenge dissolved slowly in the mouth every 3 hours as needed, up to a maximum of 12 lozenges in 24 hours. This product is not recommended for children under 6 years, as they may be unable to safely dissolve a lozenge without chewing or choking. If a dose is missed, simply take the next lozenge when needed rather than taking an extra one to make up for it. If symptoms persist beyond 3 days, worsen, or are accompanied by high fever or difficulty swallowing, stop self-treatment and see a doctor or pharmacist.

Side Effects

  • Common: Temporary numbing or tingling sensation in the mouth or throat.
  • Common: Mild burning sensation on first use.
  • Common: Dry mouth.
  • Serious: Signs of an allergic reaction such as rash, swelling of the face or throat, or difficulty breathing — seek urgent medical attention if these occur.

Contraindications

  • Known hypersensitivity to benzydamine hydrochloride, aspirin, or other NSAIDs (cross-sensitivity has been reported).
  • Not recommended for children under 6 years due to the risk of choking on a dissolving lozenge.
  • Phenylketonuria: this product contains aspartame, a source of phenylalanine, and should be avoided by patients with phenylketonuria.

Drug / Food Interactions

  • No clinically significant interactions with other oral medicines are established for benzydamine lozenges used at recommended doses.
  • Using multiple products containing benzydamine or other throat-numbing agents at the same time is not recommended, as this may increase the risk of side effects.
  • No specific food interactions are known; the lozenge is intended to dissolve in the mouth rather than being taken with food or drink.

Quick Tips

  • Let the lozenge dissolve slowly rather than biting or chewing it.
  • Keep track of the number of lozenges taken within a 24-hour period.
  • Avoid taking on an empty stomach if you notice mild stomach discomfort.
  • Keep the blister pack sealed until each lozenge is needed.
  • Note that this formulation is sugar-free, which may be relevant if you are monitoring sugar intake.
  • Store away from heat and humidity to keep the lozenge texture intact.

Ingredients / Active Ingredients

  • Active ingredient: Benzydamine Hydrochloride 2.4mg per lozenge.
  • Other ingredients: isomalt, aspartame, citric acid, and flavouring agents.
  • Sugar-free lozenge formulation, dissolved slowly in the mouth.

Relevant Information

Precautions: Use in pregnancy or while breastfeeding should only be under a doctor’s advice. Patients with a known aspirin or NSAID sensitivity, or with phenylketonuria, should check the ingredient list before use. This product is not intended for children under 6 years.

When to See a Doctor or Pharmacist: Seek medical advice if symptoms persist beyond 3 days, are accompanied by high fever, difficulty swallowing or breathing, a rash, or if any signs of an allergic reaction occur.

Frequently Asked Questions

Product Specifications

BrandDifflam
ClassificationNon-prescription
Pack Size12s
Shelf LifeUse before the expiry date printed on the pack. Do not use if the blister packaging is damaged or if a lozenge shows discolouration or an unusual texture.
Storage InstructionsStore below 25°C in a dry place, away from direct sunlight. Keep in the original blister pack until ready to use, and keep out of reach and sight of children.

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