Addison’s Disease
Overview of Addison’s Disease
Addison’s Disease is also known as primary adrenocortical insufficiency. It happens when there is either destruction or dysfunction of the adrenal cortex leading to glucocorticoid (cortisol) and mineralocorticoid (aldosterone) deficiency.
Signs and Symptoms of Addison’s Disease
Pigmented skin, Weakness, Anorexia, Dizziness, Tiredness, Abdominal pain, Diarrhea, Constipation, Nausea and vomiting, Postural hypotension,Tachycardia, Hypoglycemia, Vitiligo
Common Causes of Addison’s Disease
Autoimmunity, Tuberculosis, Adrenal metastases, Lymphoma, Opportunistic infections such as HIV, Adrenal hemorrhage
Risk Factors of Addison’s Disease
Cancer, Taking blood thinning medication, Having opportunistic infections, Surgical removal of adrenal gland, Autoimmune disease
Investigation Techniques for Addison’s Disease
Full blood count, Serum electrolytes, Serum glucose, ACTH stimulation test
Treatment and Prevention of Addison’s Disease
Hydrocortisone, Mineralocorticoids replacement
Available Addison’s Disease Medicines
No medicines currently available for this condition.
