Ankylosing Spondylitis

Medical Review

Written by: Dr. Von Chiao Wen Doctor of Medicine (MD), N.I. Pirogov Russian National Research Medical University
Reviewed by: Dr. Lee Chin Meng Doctor of Medicine (MD), Manipal Academy of Higher Education (MAHE)

Overview of Ankylosing Spondylitis

Ankylosing Spondylitis is a chronic inflammatory disease of the spine and sacroiliac joints of unknown etiology. It is more common in men than women. When it affects the spine, it causes the spine to be less flexible and results in hunching over time.

Signs and Symptoms of Ankylosing Spondylitis

Low back pain worse at night, Stiffness of the back in the morning upon waking up, Pain radiates from sacroiliac joints to the buttocks and hips, Progressive loss of spinal movements

Common Causes of Ankylosing Spondylitis

Unknown causes

Risk Factors of Ankylosing Spondylitis

Age, Male gender, Genetic factors (HLA-B27 gene), Environmental factors

Investigation Techniques for Ankylosing Spondylitis

Clinical examination of the spine and joints, MRI scan, X-ray of the affected joints, Full blood count

Treatment and Prevention of Ankylosing Spondylitis

Physiotherapy, NSAIDs, TNF alpha-blockers, Local steroid injections, Surgery

Available Ankylosing Spondylitis Medicines

No medicines currently available for this condition.

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