Microscopic Polyangiitis

Medical Review

Written by: Dr. Von Chiao Wen Doctor of Medicine (MD), N.I. Pirogov Russian National Research Medical University
Reviewed by: Dr. Lee Chin Meng Doctor of Medicine (MD), Manipal Academy of Higher Education (MAHE)

Overview of Microscopic Polyangiitis

Microscopic polyangiitis is a condition that is due to inflammation of the blood vessels which leads to multi-organ damages. However, the commonly affected organs are kidneys, lungs, skins, nerves and joints.

Signs and Symptoms of Microscopic Polyangiitis

Fever, Fatigue, Weight loss, Skin rash, Flu-like symptoms , Lungs- cough/ breathing problems/ spitting up blood , Gastrointestinal-bleeding in the gastrointestinal tract and abdominal pain , Brain/neurological-tingling/pain/weakness,/loss of sensation/ seizures , Musculoskeletal-joint pain/ muscle pain, Hypertension

Common Causes of Microscopic Polyangiitis

Genetic factor predisposing to autoimmune reaction

Risk Factors of Microscopic Polyangiitis

Occupational , Environmental , Genetic , Autoimmune conditions.

Investigation Techniques for Microscopic Polyangiitis

Complete blood cell count, Erythrocyte sedimentation rate (ESR), Renal function test, Urine FEME, Antineutrophil cytoplasmic antibody (ANCA) test, Chest radiograph, Electrocardiography , Gastrointestinal endoscopy, Electromyography, Skin biopsy

Treatment and Prevention of Microscopic Polyangiitis

Remission induction using prednisone and cyclophosphamide, Maintenance of remission with Methotrexate and Prednisone, Intravenous immunoglobulin for refractory cases

Available Microscopic Polyangiitis Medicines

No medicines currently available for this condition.

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