Polycystic Ovarian Syndrome (PCOS)

Medical Review

Written by: Dr. Von Chiao Wen Doctor of Medicine (MD), N.I. Pirogov Russian National Research Medical University
Reviewed by: Dr. Lee Chin Meng Doctor of Medicine (MD), Manipal Academy of Higher Education (MAHE)

Overview of Polycystic Ovarian Syndrome (PCOS)

Polycystic ovary syndrome is a condition that disrupts the normal hormone levels in the female. Women with this condition produce higher level of male hormones causing them several side effects such as irregular periods and most importantly, difficulty in getting pregnant (infertility).

Signs and Symptoms of Polycystic Ovarian Syndrome (PCOS)

Irregular periods, Heavy bleedin, Hirsutism, Acne, Weight gain, Darkening of the skin, Diabetes, Sleep- related problems.

Common Causes of Polycystic Ovarian Syndrome (PCOS)

Abnormal hypothalamic-pituitary-ovarian (HPO) axis, Genetic Causes, Insulin Resistance, Increased insulin production, Low-grade inflammation, Excess Androgen

Risk Factors of Polycystic Ovarian Syndrome (PCOS)

Family history of PCOS, Diabetes, Hirsutism, Infertility, Obesity and Metabolic Syndrome, Abnormal menstruation, Early menarche, Obesity, Genetic abnormalities

Investigation Techniques for Polycystic Ovarian Syndrome (PCOS)

Physical exam, Blood pressure, Pelvic exam, Pelvic ultrasound (sonogram), thyroid function tests, serum prolactin levels, a free androgen index, Blood sugar level, Lipid profile, 24-hour urine sample for free cortisol and creatinine (To rule out Cushing’s syndrome), Serum 17-hydroxyprogesterone levels (To exclude adrenal gland problem)

Treatment and Prevention of Polycystic Ovarian Syndrome (PCOS)

Low dose Combined Oral Contraceptives, Clomiphene Citrate (for infertility), Combined Metformin & Letrozole, Encourage to go on diet and exercise regimen, Laparoscopic ovarian drilling

Available Polycystic Ovarian Syndrome (PCOS) Medicines

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