Primary Biliary Cholangitis
Overview of Primary Biliary Cholangitis
Primary biliary cholangitis is a chronic condition where the bile ducts in the liver gets damaged by autoimmune granulomatous inflammation causing cholestasis which may lead to fibrosis, cirrhosis and portal hypertension.
Signs and Symptoms of Primary Biliary Cholangitis
Fatigue, Itchy skin, Dry eyes and mouth, Pain in the upper right abdomen, Swelling of the spleen, Musculoskeletal pain, Swollen feet and ankles (edema), Ascites, Xanthelasma, Jaundice
Common Causes of Primary Biliary Cholangitis
Autoimmune factor,Genetic factor,Infection with organisms of the family Enterobacteriaceae
Risk Factors of Primary Biliary Cholangitis
Female , Age 30 to 60 years old, Infections , Smoking , Toxic chemicals
Investigation Techniques for Primary Biliary Cholangitis
Full blood count, Liver function tests, Antibody tests for signs of autoimmune disease (Anti-mitochondrial antibodies (AMAs), Endoscopic retrograde cholangiopancreatography (ERCP), Magnetic resonance cholangiopancreatography (MRCP), Magnetic resonance elastography (MRE)
Treatment and Prevention of Primary Biliary Cholangitis
Ursodeoxycholic acid (UDCA), Obeticholic acid (Ocaliva), Fibrates (Tricor), Methotrexate, Colchicine, Liver transplant, Rifampin, Cholestyramine
Available Primary Biliary Cholangitis Medicines
No medicines currently available for this condition.
