Raynaud’s Disease

Medical Review

Written by: Dr. Von Chiao Wen Doctor of Medicine (MD), N.I. Pirogov Russian National Research Medical University
Reviewed by: Dr. Lee Chin Meng Doctor of Medicine (MD), Manipal Academy of Higher Education (MAHE)

Overview of Raynaud’s Disease

Raynaud’s disease is a rare condition affecting the blood vessels commonly the fingers and toes. It causes the blood vessels to constrict and narrow during cold weather or under any form of stress.

Signs and Symptoms of Raynaud’s Disease

Cold fingers or toes , Color changes in your skin , Numbness, Prickly feeling , Stinging pain

Common Causes of Raynaud’s Disease

Connective tissue diseases (systemic sclerosis, scleroderma), Diseases of the blood vessels (Nitric oxide deficiency), Certain medications including beta blockers, Nerve processing dysfuction

Risk Factors of Raynaud’s Disease

Female, Between the ages of 15 and 30, Cold climate, Family history, Associated diseases include conditions such as scleroderma and lupus, Certain occupations (vibration injury, PVC exposure).

Investigation Techniques for Raynaud’s Disease

Full blood count, Blood urea nitrogen, Creatinine, Prothrombin time Activated partial thromboplastin time, Serum glucose, Thyroid-stimulating hormone, Antinuclear antibody, Rheumatoid factor, Hepatitis panel Heavy metal screen, Serum protein and urine electrophoresis

Treatment and Prevention of Raynaud’s Disease

Alpha-1 blockers , Topical nitroglycerin ointment , Dihydropyridine calcium channel blockers , Other vasodilators (Losartan, Iloprost) , Sympathectomy , Chemical injection

Available Raynaud’s Disease Medicines

No medicines currently available for this condition.

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