Transfusion Dependent Thalassemia
Overview of Transfusion Dependent Thalassemia
Transfusion Dependent Thalassemia refers to thalassemia patients who are dependent on blood transfusion for them to be a fully functioning individual. It is also known as Thalassemia Major. It occurs due to gene defect where there’s mutation in the beta globin genes.
Signs and Symptoms of Transfusion Dependent Thalassemia
Fatigue, Weakness, Anemia (pallor), Jaundice (yellowish skin and eyes), Growth failure or retardation, Prominent forehead, Maxillary overgrowth, Malocclusion of teeth, Hepatosplenomegaly, Weak bones
Common Causes of Transfusion Dependent Thalassemia
Mutation of beta-globin genes
Risk Factors of Transfusion Dependent Thalassemia
Family history of thalassemia or anemia
Investigation Techniques for Transfusion Dependent Thalassemia
Full blood count, Full blood picture (peripheral blood picture), Hb electrophoresis, Serum ferritin, DNA analysis, Liver function test, Skull x-ray, DNA analysis
Treatment and Prevention of Transfusion Dependent Thalassemia
Blood transfusion, Iron chelation therapy, Splenectomy, Bone marrow transplantation
Available Transfusion Dependent Thalassemia Medicines
No medicines currently available for this condition.
