Ditoin 100mg Capsule

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Overview

Ditoin 100mg Capsule contains phenytoin 100mg, formulated as a capsule, a classic anticonvulsant (anti-seizure) medicine used to control tonic-clonic (grand mal) and partial (focal) seizures.

Phenytoin works by stabilising the electrical activity of overactive nerve cells in the brain, blocking sodium channels to reduce the abnormal, repetitive nerve firing that triggers a seizure.

How it Works

Phenytoin blocks voltage-gated sodium channels in nerve cells, which slows the recovery of these channels between nerve impulses. This limits the rapid, repetitive firing of neurons that occurs during a seizure, helping to stabilise electrical activity in the brain without generally suppressing normal nerve function.

Directions for Use

Swallow Ditoin 100mg Capsule whole with a glass of water, at the same time(s) each day, with or without food as advised by your doctor. Do not crush, chew, or open the capsule unless specifically instructed, and take it consistently to help maintain stable blood levels of this narrow therapeutic index medicine.

Dosage

The dose of Ditoin 100mg Capsule is individualised for each patient and is often guided by blood level monitoring (therapeutic drug monitoring), as phenytoin has a narrow therapeutic index – small dose changes can have a large effect on blood levels and seizure control. Your doctor will determine your starting dose, any adjustments, and the monitoring schedule required.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dizziness
  • Drowsiness
  • Nausea or vomiting
  • Constipation
  • Headache
  • Swollen or bleeding gums
  • Skin rash
  • Coordination problems
  • Confusion or slurred speech

Contraindications

  • Known hypersensitivity to phenytoin, other hydantoins, or any ingredient in this product
  • Certain heart rhythm conditions (e.g. sino-atrial block, second- or third-degree heart block) if given by injection
  • Concurrent use with delavirdine (an HIV medicine)

Drug / Food Interactions

  • Many medicines affect phenytoin blood levels or are affected by it, including warfarin, oral contraceptives, and certain other anticonvulsants – review all medicines with your doctor
  • Enteral (tube) feeds can significantly reduce phenytoin absorption if given at the same time – space apart as advised
  • Alcohol may affect phenytoin levels and can increase drowsiness
  • Folic acid, calcium, and vitamin D levels may be affected with long-term use – your doctor may monitor or supplement these

Quick Tips

  • Attend all scheduled blood tests for phenytoin level monitoring, especially after any dose change
  • Maintain good dental hygiene and attend regular dental check-ups to monitor for gum overgrowth
  • Never switch between different brands or formulations without your doctor’s guidance – Never switch between different brands or formulations of phenytoin without your doctor’s guidance, as this medicine has a narrow therapeutic index and bioavailability can differ meaningfully between products.
  • Take your dose consistently at the same time(s) each day
  • Report any new or worsening rash, fever, or unusual bruising to your doctor promptly
  • Do not stop this medicine abruptly, as this can trigger seizures – your doctor will advise on any changes

Frequently Asked Questions

What is Ditoin 100mg Capsule used for?

Ditoin 100mg Capsule is used to control tonic-clonic (grand mal) and partial (focal) seizures, and is sometimes used to prevent seizures around certain neurosurgical procedures.

Why do I need regular blood tests with this medicine?

Phenytoin has a narrow therapeutic index, meaning the difference between an effective dose and a dose that causes side effects is small. Regular blood level monitoring helps your doctor keep your dose in the safe and effective range.

Why does my gum health need extra attention with this medicine?

Gum overgrowth (gingival hyperplasia) is a well-known side effect of phenytoin. Maintaining good dental hygiene and seeing your dentist regularly can help manage or reduce this effect.

Can I switch to a different brand of phenytoin if it is unavailable?

No, you should not switch brands or formulations without your doctor’s guidance. Because phenytoin has a narrow therapeutic index, bioavailability can differ meaningfully between products, which may affect seizure control or increase side effects.

What should I do if I notice a rash while taking this medicine?

Contact your doctor promptly. A widespread rash, especially with fever or blistering, can be a sign of a serious skin reaction and needs urgent medical assessment.

What should I do if I miss a dose of Ditoin 100mg Capsule?

Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose, and contact your doctor if you miss doses frequently, as this can affect seizure control.

Can I buy Ditoin 100mg Capsule from DoctorOnCall?

Yes, Ditoin 100mg Capsule is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Ditoin 100mg Capsule according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Ditoin 100mg Capsule?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Ditoin 100mg Capsule cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Ditoin 100mg Capsule?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Ditoin 100mg Capsule?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Phenytoin 100mg

Safety Advice

Pregnancy

Not Advisable

Use during pregnancy is generally not recommended unless absolutely necessary.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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