Edurant 25mg tablet

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Brand Janssen
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last reviewed on

Overview

Edurant 25mg tablet is a prescription-only medicine (POM) that contains Rilpivirine 25mg (as rilpivirine hydrochloride). It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Edurant 25mg tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Edurant 25mg tablet must be taken with a meal – this is essential, as absorption is significantly reduced when taken on an empty stomach. Take it at the same time every day together with your other prescribed HIV medicines, swallowing the tablet whole with water. Do not skip meals when taking this medicine, and maintain strict, consistent adherence to your full regimen.

Dosage

The usual dose of Edurant 25mg tablet is one 25mg tablet once daily, always taken as part of a combination antiretroviral regimen determined by your HIV specialist. Never change your dose, stop, or adjust your regimen without your specialist’s guidance, as strict adherence is essential to keep the virus suppressed and prevent resistance from developing.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Nausea
  • Trouble sleeping (insomnia)
  • Depression or mood changes
  • Rash
  • Abnormal dreams
  • Dizziness

Contraindications

  • Known hypersensitivity to rilpivirine or any ingredient in this product
  • Concomitant use with proton pump inhibitors (e.g. omeprazole, esomeprazole), which significantly reduce rilpivirine absorption and effectiveness
  • Concomitant use with certain anticonvulsants (e.g. carbamazepine, phenytoin) or rifampicin, which can significantly lower rilpivirine levels
  • Concomitant use with St John’s Wort

Drug / Food Interactions

  • Proton pump inhibitors significantly reduce rilpivirine absorption and must be avoided – your HIV specialist will advise on alternative acid-suppressing options if needed
  • H2-receptor antagonists (e.g. ranitidine) and antacids can also reduce absorption and must be taken at specifically spaced times, if used at all
  • Rifampicin and certain anticonvulsants can significantly lower rilpivirine levels and are generally avoided
  • Must always be taken with food – taking it on an empty stomach significantly reduces how much medicine your body absorbs

Quick Tips

  • Always take this medicine with a meal – never on an empty stomach
  • Take all your prescribed antiretroviral medicines together, at the same time every day
  • Never stop or adjust this medicine without your HIV specialist’s guidance
  • Tell every doctor and pharmacist you see that you take rilpivirine, especially before starting any new medicine, including over-the-counter antacids
  • Do not take proton pump inhibitors while on this medicine unless your HIV specialist specifically approves it
  • Attend all scheduled viral load and specialist monitoring appointments

Ingredients / Active Ingredients

  • Rilpivirine 25mg (as rilpivirine hydrochloride)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Frequently Asked Questions

Product Specifications

BrandJanssen
ClassificationPrescription medicine
Ingredients / Active IngredientsRilpivirine
Pack Size30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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