Exforge 10/160mg Tablet
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Prescription Required
Overview
Exforge 10/160mg Tablet is a fixed-dose combination containing amlodipine 10mg (a calcium channel blocker) and valsartan 160mg (an angiotensin II receptor blocker, or ARB). It is used to treat high blood pressure (hypertension) in patients whose blood pressure is not adequately controlled with either medicine alone.
Amlodipine relaxes and widens blood vessels by blocking the entry of calcium into vascular smooth muscle cells, while valsartan blocks the action of angiotensin II, a hormone that normally narrows blood vessels. Together, these two complementary mechanisms produce a greater blood-pressure-lowering effect than either medicine used on its own.
How it Works
Amlodipine inhibits calcium influx into vascular smooth muscle, producing vasodilation and reduced peripheral resistance. Valsartan selectively blocks the AT1 receptor, preventing angiotensin II from narrowing blood vessels and triggering aldosterone release. Combining a calcium channel blocker with an ARB targets two separate blood-pressure pathways, giving more effective control while allowing lower doses of each component.
Directions for Use
Take Exforge 10/160mg Tablet at about the same time each day, with or without food. Swallow the tablet whole with a glass of water. Do not stop taking this medicine suddenly without consulting your doctor, even if you feel well, as blood pressure control needs to be continuous.
Dosage
Exforge 10/160mg Tablet is usually taken once daily. Your doctor will determine the appropriate starting dose and may adjust it based on your blood pressure response, particularly if you are switching from the individual components taken separately.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dizziness or lightheadedness
- Headache
- Swelling of hands, ankles, or feet
- Tiredness or fatigue
- Flushing (warmth and redness of the skin)
- Nausea
- Palpitations
Contraindications
- Known hypersensitivity to amlodipine, valsartan, other dihydropyridines, or any ingredient in this product
- Pregnancy (can cause harm to the developing baby, especially in the second and third trimester)
- Severe liver impairment or biliary obstruction
- Severe aortic stenosis or cardiogenic shock
- Concomitant use with aliskiren in patients with diabetes or kidney impairment
Drug / Food Interactions
- CYP3A4 inhibitors (e.g. ketoconazole, ritonavir, clarithromycin) may increase amlodipine blood levels
- Grapefruit juice may increase amlodipine levels and should be avoided
- NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
- Potassium supplements or potassium-sparing diuretics may increase the risk of high blood potassium
Quick Tips
- Take at the same time each day to build a consistent routine
- Monitor your blood pressure regularly as advised by your doctor
- Rise slowly from sitting or lying down to reduce dizziness
- Avoid grapefruit or grapefruit juice while taking this medicine
- Do not stop this medicine abruptly without medical advice
Frequently Asked Questions
What is Exforge 10/160mg Tablet used for?
Exforge 10/160mg Tablet is used to treat high blood pressure that is not fully controlled by either amlodipine or valsartan alone, combining a calcium channel blocker with an ARB in one tablet.
Why does this medicine cause ankle swelling?
Amlodipine can widen small blood vessels more than veins, which can lead to mild fluid build-up in the ankles or legs in some people. Tell your doctor if the swelling is bothersome or severe.
Can I switch to Exforge 10/160mg Tablet from my current separate blood pressure tablets?
Your doctor can guide you on switching to this combination tablet if you are already stable on the individual components at matching doses, to simplify your regimen.
How long does it take to see the full effect on blood pressure?
Some effect can be seen within the first 1-2 weeks, but the full blood-pressure-lowering effect is usually reached after about 4 weeks of regular use.
What should I do if I miss a dose of Exforge 10/160mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Exforge 10/160mg Tablet from DoctorOnCall?
Yes, Exforge 10/160mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Exforge 10/160mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Exforge 10/160mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Exforge 10/160mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Exforge 10/160mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Exforge 10/160mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Amlodipine 10mg (as amlodipine besilate)
- Valsartan 160mg
Safety Advice
Pregnancy
This medicine is not considered safe during pregnancy and should be avoided.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
