Goutnor 600mcg Tablet

Goutnor 600mcg Tablet contains colchicine, a medicine used to treat and prevent acute attacks of gout, a form of arthritis caused by the build-up of uric acid crystals in the joints. It is also used in the management of familial Mediterranean fever. Colchicine helps to reduce the intense pain, swelling, and inflammation that occur during a gout flare by interfering with the inflammatory response of white blood cells in the affected joint.

Goutnor 600mcg Tablet is a prescription-only medicine in Malaysia. It is only supplied after an online consultation with a doctor through DoctorOnCall, who will review your medical history, kidney and liver function, and other medicines you are taking before issuing a prescription, as colchicine has a narrow margin between an effective dose and a toxic one. It should be taken strictly as prescribed, with regular follow-up as advised by your doctor.

Colchicine works by binding to tubulin, a protein needed to form microtubules inside cells. This action disrupts the migration and activation of neutrophils (a type of white blood cell) into the joint, reducing the inflammatory cascade that is triggered when uric acid crystals deposit in the joint space, thereby easing the pain, redness, and swelling of a gout attack.

Goutnor 600mcg Tablet should only be taken according to the exact dose, frequency, and duration prescribed by your doctor following an online consultation with DoctorOnCall. Tablets are usually swallowed whole with a glass of water, and may be taken with or without food; taking with food may help reduce stomach upset. Do not take extra doses to relieve pain faster, as colchicine can become toxic quickly if taken in excess.

The dosage of Goutnor 600mcg Tablet is determined individually by your prescribing doctor based on whether it is being used to treat an acute gout flare or to prevent future attacks, as well as your kidney and liver function and other medicines you take. There is a maximum total dose that must not be exceeded within a defined period, and doses are often reduced in older adults or those with reduced kidney function. Always follow your prescription exactly and never adjust the dose yourself.

Goutnor 600mcg Tablet is generally stable for up to 24 to 36 months from the date of manufacture when stored correctly and unopened. Always check the expiry date printed on the blister strip or carton before use, and do not take the tablets if the date has passed.

Store Goutnor 600mcg Tablet at room temperature, below 30 degrees Celsius, in a dry place away from direct sunlight and moisture. Keep the tablets in their original packaging until ready to use, and keep well out of reach and sight of children, as colchicine can be dangerous even in small overdoses.

• Known hypersensitivity to colchicine or any ingredient in the tablet
• Severe kidney or liver impairment, especially when combined with certain other medicines
• Blood disorders affecting white cell or platelet counts
• Not recommended during pregnancy or breastfeeding unless advised by a doctor
• Use with caution in elderly patients and those with heart, kidney, or liver disease

• Strong CYP3A4 or P-glycoprotein inhibitors such as clarithromycin, certain antifungals, or ciclosporin can raise colchicine levels to dangerous levels
• Statins and fibrates taken with colchicine may increase the risk of muscle toxicity
• Grapefruit juice may increase colchicine blood levels and should be avoided
• Inform your doctor of all other medicines, supplements, and herbal products you are taking before starting Goutnor 600mcg Tablet

• Take Goutnor 600mcg Tablet exactly as prescribed and never exceed the stated maximum dose
• Report any new diarrhoea, muscle weakness, numbness, or unusual bruising to your doctor promptly
• Keep all scheduled blood tests and follow-up appointments with your doctor
• Stay well hydrated and avoid alcohol during treatment
• Seek urgent medical attention if you suspect an overdose, as colchicine toxicity can be life-threatening

Colchicine has a narrow therapeutic index, meaning the difference between an effective and a toxic dose is small, so Goutnor 600mcg Tablet must only be used under close medical supervision. Doctors will often check kidney and liver function before and during treatment, and review other medicines being taken to avoid dangerous interactions. Lifestyle measures such as limiting alcohol, reducing purine-rich foods, and maintaining a healthy weight are commonly recommended alongside medical treatment to help manage gout in the longer term.