HOE Locoa (Esflurbiprofen) 40mg Transdermal Patch

Transdermal patch containing esflurbiprofen 40mg, dispensed by a registered pharmacist.

Manufacturer HOE
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Key Information

What is HOE Locoa 40mg Transdermal Patch?

What is HOE Locoa 40mg Transdermal Patch?

  • HOE Locoa 40mg Transdermal Patch contains esflurbiprofen 40mg per patch and is supplied as a 7-patch pack.
  • It is a patch for use on the skin only, and it is not to be swallowed.
  • It is a non-prescription product, dispensed by a registered pharmacist.
  • Read the pack and leaflet before use, and use it only as directed on the label or as advised by your pharmacist.
Is this strength right for me?

Is this strength right for me?

  • HOE Locoa is available as a 40mg patch only. Check the pack and leaflet for the directions for use.
  • The patch is usually applied as one patch once daily, and you should not apply more than one patch to the same area at one time.
  • Do not use more than directed, and do not change how you use it without checking first.
  • Not sure whether it suits you? Ask our pharmacist before ordering. If you already take regular medicines or are under medical care, check with your doctor or pharmacist first.
Delivery, packaging and ordering

Delivery, packaging and ordering

  • Choose your product and place your order. No prescription is needed, and your order is dispensed by a registered pharmacist.
  • You can ask a doctor or pharmacist about the product before you buy.
  • The product page lists fast delivery, and free delivery applies with a minimum spend of RM120.
  • Each pack carries its MAL registration number from the Ministry of Health Malaysia. You can verify it through the relevant Ministry of Health resources.
Side effects, safety and when to seek help

Side effects, safety and when to seek help

  • Possible skin effects include redness, itching, skin eruption and sensitivity to light. Avoid direct sunlight or tanning lamps on the area where the patch has been applied.
  • Using it together with other medicines of the same type, such as ibuprofen or diclofenac, may increase the risk of side effects, and anticoagulants such as warfarin may increase the risk of bleeding. Tell your pharmacist or doctor about all medicines and supplements you take.
  • Do not use it on broken or irritated skin, and do not use it if you are allergic to esflurbiprofen or any ingredient in the patch.
  • Stop using it and ask your pharmacist or doctor if you feel unwell. Seek immediate medical attention for stomach pain, black stools, unusual bruising or bleeding, a widespread skin rash, swelling of the face or lips, difficulty breathing, or any severe or unexpected reaction.

How to use your HOE Locoa 40mg Transdermal Patch

  1. Step 1

    Read the pack and leaflet, and check with your pharmacist if you are unsure whether the patch suits you. Tell them about all medicines you take, any allergies, and any stomach, kidney or bleeding conditions.

  2. Step 2

    Apply the patch to clean, dry, hairless skin, pressing firmly for about 30 seconds so that it sticks well. Use a different skin site each time you change the patch, and apply only one patch at a time.

  3. Step 3

    Make a note of the day, date and time you apply the patch, so you know when to change it. Never cut or fold the patch, never apply heat over it, and wash your hands thoroughly after handling it.

  4. Step 4

    Follow the directions on the pack, and do not change how often you use it on your own. Remove the patch and ask your pharmacist or doctor if your skin becomes irritated or you feel unwell.

Delivery & Returns

  • Malaysia-wide delivery
  • No prescription needed
  • Licensed pharmacy
  • Doctor consultation

If your order arrives damaged

  • Do not use HOE Locoa Patch if the packaging is damaged, the sachet is torn or opened, or the box appears to have been tampered with.
  • Check the patches and sachets carefully before use.
  • Contact us on WhatsApp immediately and provide photos of the outer packaging and the sachets.
  • We’ll review the issue and arrange a replacement at no extra cost if the delivery issue is verified.

Returns policy

For safety reasons, HOE Locoa 40mg Transdermal Patch cannot be returned or exchanged once it has left our pharmacy, except in cases involving a verified delivery issue, such as damaged packaging, an incorrect item or a missing item.

If there is a problem with your order, contact us within 24 hours of delivery so we can review the issue and advise you on the next steps.

Chat with us on WhatsApp

Dosage

Your doctor will confirm the exact regimen, but HOE Locoa 40mg Transdermal Patch is generally applied as one patch to the affected area once daily; do not apply more than one patch to the same area at a time, and do not use for longer than the duration prescribed without a follow-up review.

Storage Instructions

Do

  • Store in a cool, dry place, following the instructions on the product packaging.
  • Keep unused patches in their sealed sachet until you use them.
  • Keep out of reach of children.
  • Check the expiry date on the packaging. Shelf life is typically 24 to 36 months from the manufacturing date.

Don't

  • Don’t leave it in a hot car, bathroom or near a stove.
  • Don’t use it after the expiry date.
  • Don’t cut, fold or apply heat over the patch.
  • Don’t share your patches with others. Dispose of used patches according to local pharmaceutical waste guidelines, folded sticky side in, and out of reach of children.

Side Effects

HOE Locoa Patch may cause side effects in some people, particularly reactions on the skin where the patch is applied. Other symptoms may also occur. Monitor the application site and pay attention to any unusual reactions during treatment.

Local Skin Reactions

Reactions may develop on the area of skin where the patch is placed, including:

  • Skin redness, itching or irritation at the application site.
  • Mild burning sensations or a skin rash where the patch was applied.

Headache

Headaches may occur in some people during treatment.

Stomach Discomfort or Nausea

Digestive discomfort or nausea may occur, although these reactions are generally less common with topical treatment than with oral NSAIDs.

Dizziness

Some people may experience dizziness during treatment.

Application Site Discomfort

Persistent discomfort or worsening skin irritation at the application site should be assessed.

Important Safety Warning

Rarely, an allergic skin reaction may occur. If you develop a significant allergic reaction:

  • Remove the patch immediately.
  • Stop using the patch and seek medical advice promptly.
  • Seek emergency medical attention if you experience facial or throat
    swelling, difficulty breathing or other signs of a severe allergic reaction.

This information does not replace the product leaflet or advice from a healthcare professional. Consult your doctor or pharmacist if symptoms persist, worsen or cause concern.

Contraindications

  • Known hypersensitivity to esflurbiprofen, flurbiprofen, aspirin, or other NSAIDs
  • History of asthma, urticaria, or allergic reactions triggered by NSAIDs or aspirin
  • Active or history of peptic ulcer or gastrointestinal bleeding
  • Severe heart, liver, or kidney impairment
  • Third trimester of pregnancy
  • Application on broken, infected, or eczematous skin

Drug / Food Interactions

  • Other oral or topical NSAIDs, or aspirin, may increase the total NSAID load and risk of side effects
  • Blood-thinning medicines (e.g., warfarin) may have an increased bleeding risk when combined with NSAIDs
  • ACE inhibitors, ARBs, or diuretics used for blood pressure may interact with NSAIDs, affecting kidney function or blood pressure control
  • Corticosteroids used together with NSAIDs can increase the risk of gastrointestinal side effects
  • Always tell your doctor about all other medicines you are taking, including supplements

Quick Tips

  • Apply to clean, dry, intact skin over the painful area for the best adhesion and absorption
  • Do not apply heat pads or hot compresses over the patch, as this can increase drug absorption
  • Rotate the application site slightly with each new patch to reduce skin irritation
  • Fold used patches sticky-side inward before disposal, as they still contain active medicine
  • Contact your doctor if pain does not improve, or if you notice stomach pain, black stools, or unusual bruising

Ingredients / Active Ingredients

  • Esflurbiprofen 40mg (active NSAID ingredient per patch)
  • Adhesive patch matrix base to hold the drug against the skin
  • Backing film/liner layers typical of transdermal patch systems
  • Permeation-enhancing excipients to support absorption through the skin

Relevant Information

The confirmed active ingredient in HOE Locoa 40mg Transdermal Patch is esflurbiprofen, an NSAID delivered through the skin — this product should not be confused with loxapine, an unrelated antipsychotic medicine with no patch formulation. As a prescription NSAID patch, ongoing use should be reviewed periodically by your doctor, especially in older adults or those with existing stomach, kidney, or heart conditions, since topical NSAIDs can still be absorbed into the bloodstream to a degree.

How to buy

Go to the DoctorOnCall website

Go to the DoctorOnCall website

Visit the DoctorOnCall website, then choose or search for HOE Locoa 40mg Transdermal Patch. Select the pack size you need, and check the quantity before adding it to your cart. If you are not sure whether it suits you, ask our pharmacist first, and read the directions on the pack and leaflet.

Place your order

Place your order

Review your cart to confirm the product, pack size and quantity. Enter your delivery address and contact details, then complete your payment securely. No prescription is needed, and you can ask a doctor or pharmacist about the product before or after you order.

Pharmacist dispenses

Pharmacist dispenses

A registered pharmacist reviews your order and prepares your medication in accordance with professional pharmacy standards. If the pharmacist needs to check anything about your order, they will contact you before it is sent out.

Receive your order

Receive your order

Your order is packed securely and delivered to your address, with fast delivery options available. When your parcel arrives, check that the packaging is intact and the product matches your order, and keep the pack and leaflet for reference. If anything looks damaged or incorrect, contact us on WhatsApp within 24 hours of delivery.

Frequently Asked Questions

Product Specifications

BrandHOE Locoa
Manufacturer Tokuhon Corporation
ClassificationNon-prescription
FormTransdermal patch
Shelf LifeTypically 24 to 36 months from the manufacturing date. Refer to the expiry date printed on the packaging. Do not use the medicine after its expiry date.
Registration holderHOE Pharmaceuticals Sdn. Bhd.
Strength40 mg per patch
Pack Size7 patches
DosageApply to clean, dry, hairless skin, pressing firmly for about 30 seconds. Follow the directions on the pack or the advice of your pharmacist.
Pack Contents1 pack of 7 patches
RouteTransdermal (on the skin only)
FrequencyUsually one patch once daily, as directed on the pack or by your pharmacist
Per Dose1 patch (40 mg)
StorageStore according to the instructions on the product packaging. Keep in a cool, dry place away from direct sunlight and excessive heat. Keep out of reach of children.
ExcipientsRefer to the package insert supplied with the product

Customer Reviews

4.7 · 10 reviews
  • Verified purchase

    Nurin Aleesyah · Purchased: 7 patches

    Product details mudah nak semak. Website pun senang digunakan dekat phone.

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