HOE U-Closone 0.05% Cream

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

HOE U-Closone 0.05% Cream is supplied as a cream, with Clobetasone Butyrate 0.05%. It is supplied in a pack size of 15g.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Apply a thin layer of HOE U-Closone 0.05% Cream to the affected area as directed by your doctor, usually once to twice daily, gently smoothing it into the skin, and wash your hands after application unless the hands are the treated area.

Dosage

The dosage, frequency, and duration of HOE U-Closone 0.05% Cream should be determined by your prescribing doctor based on the severity, extent, and location of your skin condition, with treatment typically limited to short courses to minimise the risk of steroid-related skin changes.

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight, keep the tube tightly closed, and keep out of reach and sight of children.

Side Effects

  • Mild burning or stinging at the application site
  • Dryness or cracking of the skin
  • Itching or irritation
  • Skin thinning with prolonged use
  • Changes in skin color
  • Increased hair growth in the treated area

Contraindications

  • Known hypersensitivity to clobetasone butyrate or any ingredient in the product
  • Untreated bacterial, viral, or fungal skin infections at the application site
  • Rosacea or perioral dermatitis
  • Acne vulgaris, unless specifically directed by a doctor
  • Prolonged use on the face, groin, or armpits without medical supervision

Drug / Food Interactions

  • No clinically significant food interactions have been established for topical clobetasone butyrate
  • Combining with other topical corticosteroid products may increase the risk of skin thinning and should be avoided unless a doctor advises otherwise
  • Occlusive dressings over the cream can increase absorption and the risk of side effects
  • Space out use with other topical medicines applied to the same area, or check with a doctor or pharmacist

Quick Tips

  • Apply only a thin layer; using more does not improve results
  • Use exactly as prescribed and avoid extending treatment beyond the advised duration
  • Do not bandage or wrap the treated area tightly unless instructed
  • Avoid use on the face unless specifically prescribed for that area
  • Return to your doctor if the condition does not improve or worsens after a week of treatment

Ingredients / Active Ingredients

  • Clobetasone Butyrate 0.05%
  • Cream base excipients

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Generally Safe

Generally safe, but caution may be required in some patients.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

HOE U-Closone 0.05% Cream contains clobetasone butyrate, a moderately potent topical corticosteroid that is a distinct and less potent molecule than clobetasol propionate; patients should not assume the two are interchangeable. It is intended for short-term, doctor-directed management of corticosteroid-responsive skin conditions, with monitoring recommended for use on large body surface areas, in children, or under occlusion.

Frequently Asked Questions

Product Specifications

BrandHoe Pharmaceuticals
ClassificationNon-prescription
Ingredients / Active IngredientsClobetasone Butyrate
Weight15g
Shelf LifeUse HOE U-Closone 0.05% Cream within the expiry date printed on the tube and carton, and discontinue use once this date has passed.

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Important Medical Information

💊 Recommended Dosage:

The dosage, frequency, and duration of HOE U-Closone 0.05% Cream should be determined by your prescribing doctor based on the severity, extent, and location of your skin condition, with treatment typically limited to short courses to minimise the risk of steroid-related skin changes.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to clobetasone butyrate or any ingredient in the product
  • Untreated bacterial, viral, or fungal skin infections at the application site
  • Rosacea or perioral dermatitis
  • Acne vulgaris, unless specifically directed by a doctor
  • Prolonged use on the face, groin, or armpits without medical supervision
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Mild burning or stinging at the application site
  • Dryness or cracking of the skin
  • Itching or irritation
  • Skin thinning with prolonged use
  • Changes in skin color
  • Increased hair growth in the treated area
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.