Imjudo 300mg/15ml Injection
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Prescription Required
Overview
Imjudo 300mg/15ml Injection contains tremelimumab, an immune checkpoint inhibitor (a CTLA-4-blocking monoclonal antibody) given by intravenous infusion under oncology specialist supervision, used in combination with durvalumab to treat unresectable hepatocellular carcinoma (liver cancer) and certain non-small cell lung cancers.
It works by blocking CTLA-4, a checkpoint protein that normally restrains T-cell activity. By blocking this brake, tremelimumab helps activate and expand the patient’s own T-cells so they can recognise and attack cancer cells, complementing the PD-L1-blocking action of durvalumab.
How it Works
Imjudo binds to CTLA-4 on T-cells and blocks its inhibitory signal, which otherwise dampens T-cell activation. Releasing this brake allows T-cells to become more active and expand, increasing the immune response against cancer cells when combined with a PD-L1 inhibitor.
Directions for Use
This medicine is prepared and administered only by trained healthcare professionals as an IV infusion, with monitoring for infusion-related reactions during and after each session.
Dosage
Dosing is determined by the treating oncologist as part of a combined regimen with durvalumab, then given as a timed intravenous infusion in a hospital or specialist infusion setting, typically as a single priming dose followed by durvalumab alone in subsequent cycles as directed by the oncology team.
Shelf Life
Refer to the expiry date printed on the packaging; this medicine is stored and handled only by healthcare facilities.
Storage Instructions
Stored under controlled, refrigerated conditions by the pharmacy or hospital as specified by the manufacturer; not intended for home storage.
Side Effects
- Fatigue
- Rash or itching
- Diarrhoea or colitis (bowel inflammation)
- Immune-related inflammation of organs such as the liver (hepatitis), lungs (pneumonitis), thyroid, or adrenal glands
- Infusion-related reactions
Contraindications
- Known hypersensitivity to tremelimumab or any ingredient in the formulation
- Active, uncontrolled autoimmune disease, unless specifically assessed and approved by the oncology team
Drug / Food Interactions
- Corticosteroids and other immunosuppressants may reduce effectiveness if used routinely, though sometimes needed to manage immune-related side effects under specialist guidance.
- Live vaccines are generally avoided during treatment.
- Inform your oncology team of all medicines and supplements you are taking, and of any autoimmune conditions.
Quick Tips
- Contact your care team immediately if you develop persistent diarrhoea, abdominal pain, yellowing of the skin or eyes, or unusual fatigue, as these can signal immune-related inflammation needing prompt treatment.
- Carry a note or card indicating you are receiving immunotherapy, in case of emergency care elsewhere.
- Attend all scheduled monitoring visits and blood tests.
- Report any new symptom to your oncology team rather than waiting for your next scheduled visit.
Frequently Asked Questions
What is Imjudo 300mg/15ml used for?
It is an immunotherapy medicine given together with durvalumab to treat liver cancer (hepatocellular carcinoma) and certain lung cancers.
How is this different from durvalumab alone?
It blocks a different immune checkpoint (CTLA-4) than durvalumab (which blocks PD-L1), so combining them activates the immune system through two complementary pathways.
What are immune-related side effects?
Because this medicine activates the immune system, it can sometimes cause inflammation in healthy organs such as the liver, gut, lungs, or hormone glands – these need prompt medical attention if they occur.
What symptoms should make me contact my care team urgently?
Persistent diarrhoea, yellowing of the skin or eyes, or unusual fatigue should be reported immediately.
Is this medicine given as a tablet?
No, it is given only as an intravenous infusion administered by healthcare professionals.
How often will I receive this medicine?
It is often given as a single priming dose combined with durvalumab, with durvalumab continued alone in later cycles – the exact schedule is set by your oncologist.
Can I receive vaccinations while on this treatment?
Live vaccines are generally avoided during treatment; discuss any vaccination needs with your oncology team.
Can I buy Imjudo 300mg/15ml Injection from DoctorOnCall?
Yes, Imjudo 300mg/15ml Injection is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Imjudo 300mg/15ml Injection according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Imjudo 300mg/15ml Injection?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Imjudo 300mg/15ml Injection cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Imjudo 300mg/15ml Injection?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Imjudo 300mg/15ml Injection?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Tremelimumab 300mg/15ml
Medical Review
