Iressa 250mg Tablet

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Manufacturer AstraZeneca
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Iressa 250mg Tablet contains Gefitinib 250mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Iressa 250mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take the tablet at about the same time each day, with or without food, and swallow it whole with water; if swallowing whole is difficult, ask your oncology team how it may be dispersed in water rather than crushing or chewing it yourself.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Diarrhoea
  • Skin rash or dryness
  • Nausea and vomiting
  • Loss of appetite
  • Fatigue
  • Dry mouth
  • Mild hair thinning
  • Eye irritation
  • Liver enzyme changes (observed in blood tests)

Contraindications

  • Known hypersensitivity to gefitinib or any ingredient in the tablet
  • Use in pregnancy without specialist guidance, due to potential harm to the foetus

Drug / Food Interactions

  • Strong inducers of the CYP3A4 enzyme (such as rifampicin and St John’s Wort) can lower gefitinib levels and are generally avoided.
  • Medicines that raise stomach pH (such as proton pump inhibitors) can reduce gefitinib absorption.
  • Warfarin and similar blood thinners may need closer monitoring when combined with gefitinib.
  • Inform your oncology team of all medicines and supplements you are taking.

Quick Tips

  • Contact your oncology team immediately if you develop new or worsening breathlessness, cough, or fever, as these can signal a rare but serious lung side effect.
  • Attend all scheduled liver function blood tests during treatment.
  • Use gentle skin care and tell your care team if rash becomes uncomfortable.
  • Never stop or change the dose on your own – discuss any side effects with your oncology team first.

Ingredients / Active Ingredients

  • Gefitinib 250mg

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Limited Data

Limited data is available regarding the effects of alcohol with this medicine.

Driving

Safe

This medicine does not affect your ability to drive.

Frequently Asked Questions

Product Specifications

BrandAstraZeneca
ManufacturerAstraZeneca
ClassificationPrescription medicine
Ingredients / Active IngredientsGefitinib
Pack Size30s
DosageThe usual dose is one tablet once daily, but the exact dose, duration, and any interruption is individualised and monitored by the treating oncologist based on response and side effects.
Shelf LifeRefer to the expiry date printed on the packaging.

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