Lynparza 150mg Tablet
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Prescription Required
Overview
Lynparza 150mg Tablet contains olaparib, a targeted oral cancer medicine belonging to a class called PARP inhibitors, used to treat certain ovarian, breast, pancreatic, and prostate cancers, often in patients with a BRCA gene mutation or similar DNA-repair defect confirmed by genetic testing.
It works by blocking the PARP enzyme that cancer cells rely on to repair damaged DNA. In cancer cells that already have a weakened BRCA-related DNA repair pathway, blocking PARP as well leaves the DNA damage unrepaired, causing the cancer cell to die.
How it Works
Lynparza inhibits PARP enzymes, which cancer cells use as a backup pathway to repair single-strand DNA breaks. In cells with a BRCA mutation, the main DNA-repair pathway is already impaired, so blocking PARP as well leads to an accumulation of DNA damage that the cancer cell cannot survive – an effect sometimes called “synthetic lethality”.
Directions for Use
Swallow the tablet whole with water, with or without food, at consistent times roughly 12 hours apart; do not chew, crush, dissolve, or split the tablet.
Dosage
The usual dose is 300mg (two 150mg tablets) taken twice daily, but the exact dose and any adjustment for side effects is individualised by the treating oncologist based on genetic test results, blood counts, and tolerability.
Shelf Life
Refer to the expiry date printed on the packaging.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Nausea or vomiting
- Fatigue or weakness
- Loss of appetite
- Anaemia (low red blood cell count)
- Diarrhea or constipation
- Headache
- Dizziness
- Changes in taste
- Shortness of breath
Contraindications
- Known hypersensitivity to olaparib or any ingredient in the tablet
- Breastfeeding during treatment and for a period after the last dose, as advised by the oncology team
Drug / Food Interactions
- Strong or moderate CYP3A inhibitors (such as certain antifungals and some antibiotics) can raise olaparib levels and generally require dose adjustment or avoidance.
- Strong or moderate CYP3A inducers (such as rifampicin) can lower olaparib levels and reduce its effectiveness.
- Inform your oncology team of all medicines and supplements you are taking, as many common drugs interact through this pathway.
Quick Tips
- Attend all scheduled full blood count monitoring, as this medicine can affect blood cell production over time.
- Report unusual bruising, prolonged tiredness, or repeated infections promptly, as these may need urgent evaluation.
- Take doses at consistent times about 12 hours apart to maintain steady drug levels.
- Do not start or stop any other medicine, including over-the-counter products, without checking with your oncology team first.
Frequently Asked Questions
What is Lynparza 150mg used for?
It is a targeted oral cancer medicine used to treat certain BRCA-mutated ovarian, breast, pancreatic, and prostate cancers.
Do I need genetic testing before starting this medicine?
Yes, BRCA or related gene mutation testing is generally required to confirm this medicine is appropriate for your cancer.
How does olaparib work?
It blocks a DNA-repair enzyme (PARP) that cancer cells with a BRCA mutation rely on, causing unrepaired DNA damage to build up and the cancer cell to die.
Can this medicine affect my blood counts?
Yes, it can cause anaemia and other low blood counts, and rarely a serious blood disorder, so regular blood tests are an important part of monitoring.
Can I take this with food?
Yes, it can be taken with or without food, but should be taken at consistent times about 12 hours apart.
What if I have trouble swallowing tablets?
Do not crush, chew, or split the tablet; speak with your oncology team if swallowing is difficult.
Are there medicines I should avoid while on this treatment?
Certain antifungals, antibiotics, and enzyme-inducing medicines (like rifampicin) can significantly change olaparib levels – always check with your oncology team before starting anything new.
Can I buy Lynparza 150mg Tablet from DoctorOnCall?
Yes, Lynparza 150mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Lynparza 150mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Lynparza 150mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Lynparza 150mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Lynparza 150mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Lynparza 150mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Olaparib 150mg
Safety Advice
Pregnancy
This medicine is not considered safe during pregnancy and should be avoided.
Breastfeeding
May cause serious side effects in the nursing infant. Do not use.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
