Lyrica 75mg Capsule

Lyrica 75mg Capsule contains pregabalin, an anticonvulsant medicine prescribed for neuropathic (nerve) pain conditions such as diabetic peripheral neuropathy and post-herpetic neuralgia, as an add-on treatment for certain types of epileptic seizures, and in some cases for generalised anxiety disorder or fibromyalgia, as directed by a doctor. It works on the central nervous system to calm overactive nerve signalling that causes pain, seizures, or anxiety symptoms.

Lyrica is a prescription-only medicine and, in Malaysia and many other countries, pregabalin is additionally classified as a controlled substance because of its recognised potential for misuse and physical dependence, particularly with prolonged use or at higher doses. Through DoctorOnCall, patients requiring Lyrica complete an online consultation so a doctor can confirm the diagnosis, review other medications, and issue a prescription before the order is processed.

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels on nerve endings in the central nervous system, reducing the release of excitatory neurotransmitters such as glutamate, noradrenaline, and substance P. This dampens abnormal or excessive nerve signalling, which is why pregabalin can relieve nerve-related pain, reduce seizure frequency as an add-on anticonvulsant, and ease symptoms of certain anxiety disorders.

Take Lyrica exactly as prescribed by your doctor, with or without food, swallowing the capsule whole with water; it may be taken as a single dose or divided into two to three doses throughout the day depending on the condition being treated. Never adjust your dose or stop taking Lyrica abruptly without medical advice, as sudden discontinuation after regular use can cause withdrawal symptoms such as insomnia, nausea, headache, sweating, or anxiety.

Dosage is individualised by the prescribing doctor according to the condition being treated, kidney function, and response to treatment, typically starting at a lower dose and titrated gradually upward as needed. Patients with reduced kidney function usually require a lower dose, and any changes to dosage or treatment duration should only be made under medical supervision.

Lyrica capsules are typically stable for up to 36 months from the date of manufacture when stored unopened in original packaging; always check the expiry date printed on the blister or carton before use.

Store below 30°C in a dry place away from direct sunlight and moisture, and keep out of reach of children. Do not share this medicine with anyone else, even if they have similar symptoms, given its controlled-substance status and dependence potential.

• Known hypersensitivity to pregabalin or any ingredient in the capsule
• Caution required in patients with a history of substance misuse or drug dependence, given pregabalin’s own dependence potential
• Caution in patients with significant kidney impairment, requiring dose adjustment
• Caution in pregnancy and breastfeeding — use only if the doctor determines the benefit outweighs the risk
• Caution in patients with a history of respiratory depression or those taking other sedating medicines, due to additive CNS depression

• Alcohol significantly increases dizziness, drowsiness, and impaired concentration when combined with pregabalin
• Opioid pain relievers, benzodiazepines, and other CNS depressants can add to sedation and, in combination, increase the risk of serious breathing difficulties
• Medicines that cause weight gain or fluid retention, such as certain diabetes medications (thiazolidinediones), may worsen swelling when combined with pregabalin
• No significant food interactions are expected, though taking it with food may help reduce mild stomach upset

• Avoid driving or operating machinery until you know how Lyrica affects your alertness and coordination
• Do not stop taking Lyrica suddenly; any dose reduction should be tapered gradually under a doctor’s guidance
• Avoid alcohol while taking this medicine to reduce the risk of excessive sedation
• Report any new or worsening mood changes, unusual thoughts, or swelling to your doctor promptly
• Keep this medicine secure and do not share it with others, in line with its controlled-substance status

Lyrica is an effective option for nerve pain, certain seizure types, and select anxiety or fibromyalgia presentations when used under medical supervision, but its recognised potential for dependence means treatment duration, dosing, and any tapering should always be guided by the prescribing doctor rather than self-adjusted. Patients with a personal or family history of substance misuse should discuss this openly with their doctor before starting treatment.