Mactrivir Tablet

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Manufacturer Hetero Labs
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last reviewed on

Overview

Mactrivir Tablet contains Efavirenz 600mg, Emtricitabine 200mg and Tenofovir disoproxil fumarate 300mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Mactrivir Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take the tablet on an empty stomach, preferably at bedtime, especially during the first few weeks, to reduce dizziness or vivid dreams; take it at the same time every day and do not stop or skip doses, as missed doses can lead to drug resistance.

Dosage

The usual dose is one tablet once daily, taken on an empty stomach (ideally at bedtime, especially when starting treatment, to reduce nervous-system side effects); the treating doctor confirms the dose is appropriate based on kidney function and other factors.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dizziness, vivid dreams, or difficulty sleeping, especially in the first weeks
  • Rash
  • Nausea
  • Fatigue
  • Long-term kidney and bone effects related to the tenofovir component – monitored periodically

Contraindications

  • Known hypersensitivity to efavirenz, emtricitabine, tenofovir disoproxil fumarate, or any ingredient in the tablet
  • Severe kidney impairment, unless specifically assessed by the treating doctor
  • Concurrent use with certain other medicines that interact with efavirenz – always disclose your full medicine list

Drug / Food Interactions

  • Efavirenz interacts with many other medicines, including some other HIV medicines, certain anti-tuberculosis drugs, and hormonal contraceptives – always check with your doctor before starting anything new.
  • St John’s Wort can significantly lower efavirenz levels and should be avoided.
  • Other medicines that affect kidney function should be used cautiously due to the tenofovir component.
  • Inform your doctor of all medicines and supplements you are taking.

Quick Tips

  • Take this medicine at the same time every day without missing doses – consistent adherence is essential to prevent drug resistance.
  • Taking it at bedtime on an empty stomach can help reduce dizziness and vivid dreams in the first weeks.
  • Attend scheduled kidney function and bone health monitoring as advised by your doctor.
  • Do not stop this medicine on your own; discuss any side effects or concerns with your doctor first.

Ingredients / Active Ingredients

  • Efavirenz 600mg
  • Emtricitabine 200mg
  • Tenofovir disoproxil fumarate 300mg

Frequently Asked Questions

Product Specifications

ManufacturerHetero Labs
ClassificationPrescription medicine
Pack Size30s
Shelf LifeRefer to the expiry date printed on the packaging.

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