Madopar 250mg Tablet

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Brand Roche
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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Madopar 250mg Tablet is a prescription-only medicine (POM) that contains Levodopa 200mg and Benserazide 50mg (as benserazide hydrochloride). It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Madopar 250mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Swallow Madopar 250mg Tablet whole with a glass of water, generally about 30 minutes to an hour before meals, or as directed by your doctor, since protein-rich meals can reduce levodopa absorption. Take it at consistent times each day, as your doctor will build up a personalised dosing schedule (often several doses a day) to keep your symptoms controlled throughout the day.

Dosage

The dose of Madopar 250mg Tablet is individualised by your doctor, usually starting low and increasing gradually based on your symptom response and tolerance, often divided into several doses across the day to maintain steady symptom control. Never adjust your dose or dosing schedule without your doctor’s guidance, as both under- and over-treatment can worsen Parkinson’s symptoms or cause side effects.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

Levodopa

  • Nausea or vomiting
  • Dizziness or lightheadedness
  • Sleep disturbances
  • Involuntary movements (dyskinesia)
  • Dry mouth
  • Low blood pressure when standing
  • Confusion or mood changes

Benserazide

  • Nausea
  • Dizziness or light-headedness
  • Dry mouth
  • Abnormal body movements (dyskinesia)
  • Sleep disturbances
  • Low blood pressure when standing (orthostatic hypotension)

Contraindications

  • Known hypersensitivity to levodopa, benserazide, or any ingredient in this product
  • Severe psychiatric disorders with psychosis
  • Severe cardiac, hepatic, or renal impairment
  • Narrow-angle glaucoma
  • Concurrent use with non-selective monoamine oxidase (MAO) inhibitors

Drug / Food Interactions

  • Non-selective MAO inhibitors must not be combined with this product due to the risk of a hypertensive reaction
  • Antipsychotic medicines and metoclopramide may reduce the effectiveness of levodopa by blocking dopamine receptors
  • High-protein meals taken at the same time may reduce levodopa absorption and effectiveness
  • Iron supplements may reduce levodopa absorption if taken at the same time – space doses apart

Quick Tips

  • Take doses at consistent times to help maintain steady symptom control throughout the day
  • Do not stop this medicine suddenly – abrupt withdrawal can cause a serious worsening of Parkinson’s symptoms
  • Rise slowly from sitting or lying down to reduce dizziness
  • Keep a symptom diary to help your doctor fine-tune your dosing schedule
  • Tell your doctor promptly about new involuntary movements, hallucinations, or confusion

Frequently Asked Questions

Is Madopar 250mg Tablet a prescription medicine?

Yes. Madopar 250mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Madopar 250mg Tablet contain?

Madopar 250mg Tablet is supplied as a tablet and contains Levodopa 200mg and Benserazide 50mg (as benserazide hydrochloride). The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Madopar 250mg Tablet is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Madopar 250mg Tablet?

Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Madopar 250mg Tablet?

Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Madopar 250mg Tablet on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Madopar 250mg Tablet?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.

Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Madopar 250mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Madopar 250mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Levodopa 200mg
  • Benserazide 50mg (as benserazide hydrochloride)

Safety Advice

Levodopa

Pregnancy

Limited Data

Limited information is available regarding use during pregnancy. Use only if clearly needed.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Benserazide

Pregnancy

No Data

There is no adequate data on use during pregnancy. Consult a doctor before use.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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