Metgyl 400mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Metgyl 400mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Metronidazole 400mg as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Swallow Metgyl 400mg Tablet tablets whole with a full glass of water, taken with food if it upsets the stomach, at the times your doctor has specified. Complete the entire course even if you feel better before it is finished. Avoid alcohol during treatment and for at least 48 hours after the last dose, as combining the two can cause an unpleasant reaction (flushing, nausea, palpitations).

Dosage

The usual adult dose of Metgyl 400mg Tablet depends on the infection being treated – courses for anaerobic bacterial infections are typically given several times a day for around 5-7 days, while some conditions use a different regimen. Your doctor will determine the exact dose, frequency, and duration for your specific infection, and the full course should be completed even if you start to feel better.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Metallic taste in the mouth
  • Headache
  • Diarrhea or stomach upset
  • Dizziness
  • Dark-colored urine
  • Mild skin rash

Contraindications

  • Known hypersensitivity to metronidazole or other nitroimidazole derivatives
  • First trimester of pregnancy, unless specifically advised by your doctor
  • Concomitant use of disulfiram or use within the past two weeks
  • Active consumption of alcohol during and shortly after treatment

Drug / Food Interactions

  • Alcohol can cause a disulfiram-like reaction (flushing, nausea, palpitations) – avoid during treatment and for 48 hours after the last dose
  • Warfarin’s blood-thinning effect may be enhanced, requiring closer monitoring of clotting (INR) tests
  • Lithium blood levels may increase when combined with metronidazole
  • Disulfiram must not be combined, as it can cause a psychotic reaction; cimetidine may increase metronidazole blood levels

Quick Tips

  • Complete the full course even if you feel better before it is finished
  • Avoid alcohol during treatment and for 48 hours after the last dose
  • Take with food if it upsets your stomach
  • A metallic taste is common and temporary
  • Report any numbness or tingling in your hands or feet to your doctor

Ingredients / Active Ingredients

  • Metronidazole 400mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Safe

It is not safe to consume alcohol with this medicine as it may cause adverse effects.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

ClassificationPrescription medicine
Ingredients / Active IngredientsMetronidazole
Pack Size10s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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