Natacyn (Natamycin) 5% Eye Suspension

Brand Alcon
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Natacyn (Natamycin) 5% Eye Suspension is an oral suspension with Natamycin 5% w/v declared as its active content. It is supplied in a pack size of 15ml.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Natacyn must be used exactly as directed by your ophthalmologist, as fungal keratitis treatment schedules are individualised and often intensive in the initial phase. Shake the suspension well before each use. Instil the prescribed number of drops into the affected eye without letting the dropper touch the eye or any surface, and attend all scheduled follow-up examinations so your specialist can monitor the infection’s response to treatment, since fungal infections can be slow to resolve and require careful reassessment.

Dosage

A commonly used regimen for fungal keratitis is one drop instilled into the conjunctival sac every 1 to 2 hours initially, which may be reduced to one drop 6 to 8 times daily after the first 3 to 4 days as directed by your specialist, with total treatment typically continuing for 2 to 3 weeks or longer depending on clinical response. Dosing and duration must be individualised by your treating doctor based on the severity of the infection and its response to treatment; do not adjust the schedule yourself.

Shelf Life

Use before the expiry date printed on the carton and bottle. Once opened, the suspension should generally be used within the timeframe stated by your pharmacist (commonly around 4 weeks), and any change in colour or consistency should prompt you to stop use and check with your pharmacist.

Storage Instructions

Store in a refrigerator between 2°C and 8°C unless the product information specifies otherwise, and protect from light. Do not freeze. Shake well before use if the suspension has settled, and keep out of the reach and sight of children.

Side Effects

  • Temporary eye irritation or redness
  • Blurred vision after application
  • Eye discomfort or itching
  • Tearing or watery eyes
  • Mild allergic reaction (rare)

Contraindications

  • Known hypersensitivity to natamycin or any component of the suspension
  • Should not be used to self-treat a red or painful eye without a confirmed diagnosis, as fungal keratitis requires specific identification and misdiagnosis can delay proper treatment
  • Not a substitute for surgical or other specialist interventions that may be needed in severe or non-responding fungal keratitis
  • Use with caution and close monitoring in contact lens wearers, and contact lenses should generally not be worn during active treatment

Drug / Food Interactions

  • If other eye medications are prescribed alongside Natacyn (such as additional antimicrobial or antifungal agents), your doctor will specify the order and spacing of administration, generally at least 5 to 10 minutes apart
  • Concurrent use of topical corticosteroid eye drops is generally avoided or used only under very close specialist supervision, as steroids may worsen fungal infections
  • Inform your specialist of all other eye drops, contact lens solutions, or systemic medicines you are using
  • No specific food interactions are known for this topical eye medicine

Quick Tips

  • Attend every follow-up appointment with your ophthalmologist, as fungal keratitis needs regular clinical reassessment of treatment response
  • Shake the bottle well before each use since Natacyn is a suspension, not a clear solution
  • Do not stop treatment early even if your eye feels more comfortable, as fungal infections often require prolonged therapy
  • Avoid wearing contact lenses during treatment unless your specialist specifically advises otherwise
  • Seek urgent review if pain worsens, vision deteriorates, or the eye becomes more red or swollen despite treatment
  • Store in the refrigerator and shake well, checking the appearance of the suspension before each use

Ingredients / Active Ingredients

  • Natamycin 5% w/v (active ingredient)
  • Benzalkonium chloride (preservative)
  • Suspending agents to maintain even dispersion of the active ingredient
  • Tonicity and buffering agents
  • Purified water as the vehicle base

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Generally Safe

Generally safe, but caution may be required in some patients.

Alcohol

Generally Safe

Consuming alcohol with this medicine is generally safe, but moderate intake is advised.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Fungal keratitis is a serious eye condition that can threaten vision if not properly treated, and confirming the diagnosis often requires specialist examination and sometimes laboratory testing of a corneal sample. Treatment courses with Natacyn are typically longer than for bacterial eye infections, and response is judged clinically by your ophthalmologist over repeated visits rather than by symptom relief alone, since the eye may still be improving even if some discomfort persists. Risk factors for fungal keratitis include eye injury involving plant material or soil, prolonged or improper contact lens wear, and pre-existing corneal disease, so specialist follow-up is essential throughout treatment.

Frequently Asked Questions

Product Specifications

BrandAlcon
ClassificationNon-prescription
Ingredients / Active IngredientsNatamycin
Volume15ml

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Important Medical Information

💊 Recommended Dosage:

A commonly used regimen for fungal keratitis is one drop instilled into the conjunctival sac every 1 to 2 hours initially, which may be reduced to one drop 6 to 8 times daily after the first 3 to 4 days as directed by your specialist, with total treatment typically continuing for 2 to 3 weeks or longer depending on clinical response. Dosing and duration must be individualised by your treating doctor based on the severity of the infection and its response to treatment; do not adjust the schedule yourself.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to natamycin or any component of the suspension
  • Should not be used to self-treat a red or painful eye without a confirmed diagnosis, as fungal keratitis requires specific identification and misdiagnosis can delay proper treatment
  • Not a substitute for surgical or other specialist interventions that may be needed in severe or non-responding fungal keratitis
  • Use with caution and close monitoring in contact lens wearers, and contact lenses should generally not be worn during active treatment
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Temporary eye irritation or redness
  • Blurred vision after application
  • Eye discomfort or itching
  • Tearing or watery eyes
  • Mild allergic reaction (rare)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.