Nexpro 40mg Tablet
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Prescription Required
Overview
Nexpro 40mg Tablet contains esomeprazole 40mg, a proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), stomach and duodenal ulcers, and conditions of excess stomach acid production. It is also used together with antibiotics to help eradicate Helicobacter pylori infection.
Esomeprazole works by blocking the proton pumps in the stomach lining that produce acid, which reduces the amount of acid in the stomach and allows the oesophagus or ulcers to heal.
How it Works
Esomeprazole irreversibly binds to and inhibits the H+/K+-ATPase (proton pump) in the parietal cells of the stomach lining, the final step in gastric acid secretion. This significantly reduces both basal and stimulated stomach acid production, allowing irritated or ulcerated tissue to heal.
Directions for Use
Take Nexpro 40mg Tablet at least 1 hour before a meal, usually in the morning, swallowing the tablet whole with a glass of water – do not crush or chew it. Continue the full course as prescribed even if your symptoms improve early, unless your doctor advises otherwise.
Dosage
The usual dose of Nexpro 40mg Tablet for GERD is 40mg once daily for 4-8 weeks, or 20mg once daily for maintenance therapy, adjusted by your doctor depending on the condition being treated and your response. For H. pylori eradication, it is used together with antibiotics for a shorter, specific course. Always take exactly as prescribed.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Headache
- Diarrhoea or constipation
- Abdominal pain
- Nausea or vomiting
- Bloating or gas
- Dizziness
- Dry mouth
Contraindications
- Known hypersensitivity to esomeprazole, other proton pump inhibitors, or any ingredient in this product
- Concomitant use with nelfinavir or rilpivirine-containing HIV medicines
Drug / Food Interactions
- Clopidogrel’s antiplatelet effect may be reduced when taken with esomeprazole
- Certain HIV medicines (e.g. atazanavir, nelfinavir) may have reduced absorption when combined with esomeprazole
- Methotrexate levels may increase, particularly at high-dose methotrexate regimens
- Long-term use may reduce absorption of vitamin B12 and magnesium
Quick Tips
- Take about 1 hour before a meal for the best effect
- Complete the full prescribed course, even for H. pylori eradication regimens combined with antibiotics
- Avoid trigger foods that worsen reflux, such as fatty, spicy, or acidic foods, and avoid lying down right after eating
- Inform your doctor if you need to use this medicine for a prolonged period, as periodic review may be recommended
Frequently Asked Questions
What is Nexpro 40mg Tablet used for?
Nexpro 40mg Tablet is used to treat acid reflux (GERD), stomach and duodenal ulcers, and excess stomach acid conditions, and is also used with antibiotics to help eradicate H. pylori infection.
When is the best time to take this medicine?
Esomeprazole works best when taken about 1 hour before a meal, usually in the morning, as this allows the medicine to be active when the proton pumps are most stimulated by food.
How long does it take for symptoms to improve?
Many people notice improvement in reflux symptoms within a few days, but it can take up to 4-8 weeks of regular use to fully heal the oesophagus or an ulcer, so complete the full course as prescribed.
Can I take this medicine long-term?
Esomeprazole can be used long-term when prescribed by your doctor, but prolonged use should be periodically reviewed, as it may be associated with reduced absorption of vitamin B12 and magnesium over time.
What should I do if I miss a dose of Nexpro 40mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Nexpro 40mg Tablet from DoctorOnCall?
Yes, Nexpro 40mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Nexpro 40mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Nexpro 40mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Nexpro 40mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Nexpro 40mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Nexpro 40mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Esomeprazole 40mg (as esomeprazole magnesium trihydrate)
Safety Advice
Pregnancy
There is no adequate data on use during pregnancy. Consult a doctor before use.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
No data is available regarding the interaction of alcohol with this medicine.
Driving
This medicine is generally safe and should not impair your driving ability.
Medical Review
