Nexium 40mg Tablet

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Nexium 40mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Esomeprazole 40mg (as esomeprazole magnesium trihydrate) as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Nexium 40mg Tablet once daily, at least one hour before a meal, swallowing the tablet whole with a glass of water. Do not crush, chew, or split the tablet, as this would destroy the coating that protects the medicine from stomach acid before it is absorbed.

Dosage

The usual adult dose of Nexium 40mg Tablet is one tablet once daily, though your doctor may adjust the dose and duration depending on the condition being treated – for example, H. pylori eradication regimens are typically shorter courses, while GERD maintenance treatment may continue for longer. Always follow your doctor’s specific instructions.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Diarrhoea or constipation
  • Abdominal pain
  • Nausea or vomiting
  • Bloating or gas
  • Dizziness
  • Dry mouth

Contraindications

  • Known hypersensitivity to esomeprazole or other proton pump inhibitors (including substituted benzimidazoles)
  • Concurrent use with nelfinavir, an HIV medicine that requires stomach acid for absorption

Drug / Food Interactions

  • Clopidogrel’s antiplatelet effect may be reduced when combined with esomeprazole, as both are metabolised via the CYP2C19 enzyme – discuss with your doctor if you take clopidogrel
  • Reduces absorption of medicines that require an acidic stomach environment, such as ketoconazole and atazanavir
  • Methotrexate blood levels may increase when combined with high-dose esomeprazole, particularly with high-dose methotrexate regimens
  • Digoxin absorption may be altered, and long-term use may reduce absorption of vitamin B12, calcium, and magnesium

Quick Tips

  • Take at least one hour before a meal for the most consistent acid-suppressing effect
  • Swallow the tablet whole – do not crush, chew, or split it
  • Report severe or persistent diarrhoea to your doctor, especially if it develops during or after treatment
  • Discuss any long-term use with your doctor, as prolonged PPI therapy is periodically reviewed
  • Inform your doctor if you are taking clopidogrel, methotrexate, or HIV medicines

Frequently Asked Questions

Is Nexium 40mg Tablet a prescription medicine?

Yes. Nexium 40mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Nexium 40mg Tablet contain?

Nexium 40mg Tablet is supplied as a tablet and contains Esomeprazole 40mg (as esomeprazole magnesium trihydrate). The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Nexium 40mg Tablet is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Nexium 40mg Tablet?

Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Nexium 40mg Tablet?

Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Nexium 40mg Tablet on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Nexium 40mg Tablet?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.

Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Nexium 40mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Nexium 40mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Esomeprazole 40mg (as esomeprazole magnesium trihydrate)

Safety Advice

Pregnancy

No Data

There is no adequate data on use during pregnancy. Consult a doctor before use.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

No Data

No data is available regarding the interaction of alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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