Nolvadex-D 20mg Tablet
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Overview
Nolvadex-D 20mg Tablet contains tamoxifen 20mg, a selective estrogen receptor modulator (SERM) used mainly in the treatment of oestrogen-receptor-positive breast cancer. It is a specialist oncology medicine that must be prescribed and monitored by an oncologist or breast specialist, never self-initiated or self-adjusted.
Tamoxifen works by competitively binding to oestrogen receptors on breast tissue cells, blocking oestrogen from attaching to these receptors and stimulating the growth of hormone-sensitive breast cancer cells. In some other tissues, such as the uterus and bone, tamoxifen instead behaves more like a weak oestrogen, which explains both some of its benefits and some of its specific risks.
How it Works
Tamoxifen acts as an anti-oestrogen in breast tissue by occupying oestrogen receptors and blocking oestrogen-driven signalling that would otherwise promote the growth of hormone-sensitive breast cancer cells, while behaving as a partial oestrogen agonist in tissues such as the endometrium and bone, which is why regular gynaecological and bone health monitoring is part of routine care during treatment.
Directions for Use
Take Nolvadex-D 20mg Tablet at about the same time each day, with or without food, swallowing the tablet whole with a glass of water. Take it regularly as part of your ongoing cancer treatment plan, and keep all scheduled oncology follow-up appointments so your specialist can monitor your response and any side effects.
Dosage
The usual dose of Nolvadex-D 20mg Tablet is 20mg once daily, though your oncologist will confirm the exact dose and duration of treatment (often several years) based on your specific cancer type, stage, and treatment plan. Never change your dose or stop treatment without your specialist’s explicit instruction, as tamoxifen is typically part of a long-term cancer treatment or prevention strategy.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Hot flashes
- Nausea or upset stomach
- Fatigue or tiredness
- Menstrual irregularities
- Headache
- Vaginal dryness or discharge
- Mood changes
- Leg cramps
Contraindications
- Known hypersensitivity to tamoxifen or any ingredient in this product
- Pregnancy (tamoxifen can harm the developing baby)
- Concurrent use with warfarin without close specialist monitoring (increased bleeding risk)
- History of venous thromboembolism (blood clots) except where the benefits of treatment are judged by your oncologist to outweigh this risk
Drug / Food Interactions
- Warfarin’s blood-thinning effect can be significantly increased by tamoxifen, requiring closer INR monitoring
- Certain antidepressants that strongly inhibit CYP2D6 (e.g. paroxetine, fluoxetine) may reduce the conversion of tamoxifen to its active form and potentially reduce its effectiveness – discuss any antidepressant use with your oncologist
- Rifampicin and phenytoin may reduce tamoxifen blood levels
- Inform your oncologist of all medicines and supplements you are taking, as several drugs can affect tamoxifen’s metabolism
Quick Tips
- Attend all scheduled oncology follow-up visits, including gynaecological and bone health monitoring as advised
- Report any abnormal vaginal bleeding, leg swelling, or breathlessness to your doctor promptly
- Never stop or change your dose without your oncologist’s explicit instruction
- Discuss any new medicine, including antidepressants and over-the-counter products, with your oncologist before starting it
- Keep a record of your treatment duration, as tamoxifen is often prescribed for several years as part of a long-term plan
Frequently Asked Questions
What is Nolvadex-D 20mg Tablet used for?
Nolvadex-D 20mg Tablet is used to treat oestrogen-receptor-positive breast cancer and to reduce the risk of recurrence after breast cancer surgery, and in certain cases to reduce the risk of developing breast cancer in high-risk individuals, always as part of a specialist oncology treatment plan.
How long will I need to take this medicine?
Treatment duration varies and is decided by your oncologist based on your specific cancer type and stage, but tamoxifen is commonly prescribed for several years (often 5-10 years) as part of long-term hormonal therapy.
Why do I need regular gynaecological check-ups while on this medicine?
Tamoxifen can have oestrogen-like effects on the lining of the uterus (endometrium) in some patients, so regular gynaecological monitoring helps your specialist detect and manage any changes early.
Can I take this medicine if I am pregnant or planning pregnancy?
No, tamoxifen should not be used during pregnancy as it can harm the developing baby. Discuss effective non-hormonal contraception with your oncologist, as tamoxifen itself is not a contraceptive and can still permit pregnancy in premenopausal women.
What symptoms should prompt me to contact my doctor urgently?
Contact your doctor or oncology team immediately if you experience leg swelling or pain, sudden breathlessness or chest pain, unexpected vaginal bleeding, or new visual changes, as these can signal serious side effects requiring urgent assessment.
What should I do if I miss a dose of Nolvadex-D 20mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose, and inform your oncology team if you miss doses frequently.
Can I buy Nolvadex-D 20mg Tablet from DoctorOnCall?
Yes, Nolvadex-D 20mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Nolvadex-D 20mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Nolvadex-D 20mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Nolvadex-D 20mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Nolvadex-D 20mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Nolvadex-D 20mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Tamoxifen 20mg (as tamoxifen citrate)
Safety Advice
Pregnancy
Use during pregnancy is generally not recommended unless absolutely necessary.
Breastfeeding
Generally not recommended while breastfeeding.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
Medical Review
