Nuelin SR 250mg Tablet

Nuelin SR 250mg Tablet contains Theophylline 250mg and is presented as a tablet. It is supplied in a pack size of 20s.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Nuelin SR 250mg Tablet must be taken exactly as prescribed by your doctor, at the same times each day to maintain steady blood levels, generally with a full glass of water. Swallow the tablet whole; do not crush, chew, or break it, as doing so can disrupt the sustained-release mechanism and cause too much theophylline to be released at once, raising the risk of toxicity. Taking it consistently in relation to meals (as advised by your doctor) helps maintain stable absorption from dose to dose.

Dosage of Nuelin SR 250mg Tablet is individualised by your doctor based on body weight, smoking status, liver function, other medicines you are taking, and periodic blood theophylline level results, and must never be adjusted or stopped by the patient without medical advice. Typical adult maintenance regimens involve twice-daily dosing, but the exact dose, timing, and any changes will be determined by your prescribing doctor, with blood tests used to keep levels within the safe therapeutic range and to guide dose adjustments.

Do not use this medicine beyond the expiry date stated on the packaging. Your pharmacist can confirm the exact expiry date at the time of dispensing.

Store below 30°C in a dry place away from direct sunlight and moisture, and keep the tablets in their original packaging until use. Keep out of the sight and reach of children at all times.

• Known hypersensitivity to theophylline or other xanthine derivatives such as aminophylline or caffeine-based compounds.
• Uncontrolled seizure disorders.
• Active peptic ulcer disease, unless specifically advised by your doctor.
• Uncontrolled cardiac arrhythmias.
• Should not be started, stopped, or dose-adjusted without a doctor’s supervision due to the narrow therapeutic index.

• Certain antibiotics (such as ciprofloxacin, erythromycin) and antifungals can raise theophylline blood levels significantly, increasing toxicity risk.
• Smoking and some anti-seizure medicines (such as phenytoin, carbamazepine) can lower theophylline levels, potentially reducing effectiveness.
• Caffeine-containing foods and drinks may add to stimulant-type side effects such as jitteriness or palpitations.
• Other bronchodilators, diuretics, and certain heart medicines may interact with theophylline; always inform your doctor of all medicines and supplements you are taking.
• Changes in smoking habits (starting or stopping) can significantly alter theophylline blood levels and may require dose adjustment by your doctor.

• Take this medicine only as prescribed and attend all scheduled blood tests to monitor your theophylline level.
• Never crush, chew, or split the tablet — swallow it whole.
• Tell your doctor about all other medicines, supplements, and your smoking status, as these can affect theophylline levels.
• Report symptoms such as persistent nausea, vomiting, palpitations, or restlessness to your doctor promptly.
• Do not stop this medicine suddenly without medical advice, as your asthma or COPD control may worsen.
• Keep consistent timing of doses each day to maintain steady blood levels.

Precautions: Theophylline requires careful dosing and monitoring in the elderly, in those with liver disease, heart failure, or fever, and in smokers versus non-smokers, as these factors affect how the body processes the drug. Regular blood level monitoring is important, especially after any change in dose, other medicines, or smoking habits.

When to See a Doctor or Pharmacist: Contact your doctor promptly if you experience nausea, vomiting, rapid or irregular heartbeat, tremor, seizures, or confusion, or if your asthma/COPD symptoms are not well controlled, as your dose or monitoring schedule may need to be reviewed.