Pharmaniaga Ciprofloxacin 500mg Tablet

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Overview

Pharmaniaga Ciprofloxacin 500mg Tablet contains ciprofloxacin 500mg, a fluoroquinolone antibiotic used to treat a range of bacterial infections, including urinary tract, gastrointestinal, respiratory, and certain skin and bone/joint infections. It is generally reserved for infections where other antibiotic classes are unsuitable, ineffective, or where broader Gram-negative coverage is needed.

Ciprofloxacin works by blocking bacterial enzymes (DNA gyrase and topoisomerase IV) that bacteria need to copy and repair their DNA. Without functioning DNA, the bacteria cannot grow or multiply, which stops the infection from progressing.

How it Works

Ciprofloxacin inhibits DNA gyrase and topoisomerase IV, two enzymes bacteria rely on to unwind, replicate, and repair their DNA during growth and division. By blocking these enzymes, ciprofloxacin prevents the bacteria from copying their genetic material, which halts bacterial growth and leads to bacterial death.

Directions for Use

Take Pharmaniaga Ciprofloxacin 500mg Tablet with a full glass of water, with or without food. Antacids, and products containing calcium, iron, zinc, or dairy products (such as milk or yoghurt), significantly reduce how well ciprofloxacin is absorbed if taken at or around the same time, so these should be taken at least 2 hours before or 6 hours after your dose of ciprofloxacin.

Dosage

The dose and duration of Pharmaniaga Ciprofloxacin 500mg Tablet depend on the type and severity of infection being treated, but a common adult dose is 500mg twice daily for a course typically lasting 3-14 days depending on the infection. Always complete the full course exactly as prescribed by your doctor, even if you feel better before it is finished.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhoea
  • Headache or dizziness
  • Rash or skin irritation
  • Joint or muscle pain
  • Increased sensitivity to sunlight
  • Trouble sleeping or restlessness

Contraindications

  • Known hypersensitivity to ciprofloxacin or other fluoroquinolone antibiotics
  • Personal or family history of tendon disorders related to fluoroquinolone use
  • Concurrent use with tizanidine
  • Caution required in patients with a known heart rhythm abnormality (QT prolongation), a history of seizures, or myasthenia gravis
  • Generally avoided in children, pregnancy, and breastfeeding unless clearly necessary, due to potential effects on developing joints/cartilage

Drug / Food Interactions

  • Antacids, and calcium, iron, zinc, or dairy products significantly reduce ciprofloxacin absorption if taken together – space doses at least 2 hours before or 6 hours after
  • Corticosteroids (e.g. prednisolone) combined with ciprofloxacin further increase the risk of tendon problems, especially in older patients
  • Theophylline levels may increase significantly when combined with ciprofloxacin, raising the risk of toxicity
  • Warfarin’s blood-thinning effect may be enhanced, requiring closer INR monitoring

Quick Tips

  • Space out antacids, calcium, iron, zinc supplements, and dairy products from your ciprofloxacin dose by several hours to avoid reduced absorption
  • Stop the medicine and contact your doctor immediately if you notice tendon pain, swelling, or weakness, especially around the Achilles tendon at the back of the ankle
  • Complete the full course of antibiotics exactly as prescribed, even if you feel better early
  • Avoid excessive sun exposure, as fluoroquinolones can increase sensitivity to sunlight
  • Older patients and those taking corticosteroids should be especially alert for tendon symptoms
  • Do not share this antibiotic with anyone else, and do not use leftover doses for a different illness

Frequently Asked Questions

What is Pharmaniaga Ciprofloxacin 500mg Tablet used for?

Pharmaniaga Ciprofloxacin 500mg Tablet is a fluoroquinolone antibiotic used to treat various bacterial infections, including urinary tract, gastrointestinal, respiratory, and certain skin, bone, or joint infections. Your doctor will confirm the specific infection it has been prescribed for.

Why can’t I take antacids or milk at the same time as this medicine?

Antacids and products containing calcium, iron, zinc, or dairy significantly reduce how well ciprofloxacin is absorbed into your body if taken too close together. Space these at least 2 hours before or 6 hours after your dose to avoid reducing its effectiveness.

What are the warning signs of a tendon problem with this medicine?

Fluoroquinolone antibiotics like ciprofloxacin carry a well-documented risk of tendinitis and tendon rupture, particularly affecting the Achilles tendon, and especially in older patients or those taking corticosteroids. Stop the medicine and contact your doctor immediately if you notice sudden tendon pain, swelling, or weakness.

Can I take this medicine if I am also on a steroid medicine?

Combining ciprofloxacin with corticosteroids further increases the risk of tendon problems, particularly in older patients. Tell your doctor if you are taking any steroid medicines before starting ciprofloxacin.

What should I do if I miss a dose of Pharmaniaga Ciprofloxacin 500mg Tablet?

Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.

Can I buy Pharmaniaga Ciprofloxacin 500mg Tablet from DoctorOnCall?

Yes, Pharmaniaga Ciprofloxacin 500mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Pharmaniaga Ciprofloxacin 500mg Tablet according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Pharmaniaga Ciprofloxacin 500mg Tablet?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Pharmaniaga Ciprofloxacin 500mg Tablet cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Pharmaniaga Ciprofloxacin 500mg Tablet?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Pharmaniaga Ciprofloxacin 500mg Tablet?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Ciprofloxacin 500mg (as ciprofloxacin hydrochloride)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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