Pharmaniaga Cloxacilla 250mg Capsule

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Pharmaniaga Cloxacilla 250mg Capsule is a prescription-only medicine (POM) that contains Cloxacillin 250mg (as cloxacillin sodium). It is supplied as a capsule and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Pharmaniaga Cloxacilla 250mg Capsule is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Pharmaniaga Cloxacilla 250mg Capsule on an empty stomach, at least 1 hour before or 2 hours after food, as food in the stomach can significantly reduce how well cloxacillin is absorbed. Swallow the capsule whole with a full glass of water, and try to space your doses evenly throughout the day.

Dosage

The dose and duration of Pharmaniaga Cloxacilla 250mg Capsule depend on the site and severity of the infection, but a common adult dose is 250mg to 500mg four times daily for 5-10 days. Always complete the full course exactly as prescribed by your doctor, even if your symptoms improve before the course is finished.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhoea
  • Rash or skin irritation
  • Abdominal discomfort
  • Allergic reactions (such as itching or swelling)
  • Headache

Contraindications

  • Known hypersensitivity to cloxacillin or other penicillin antibiotics
  • History of a severe allergic reaction to any beta-lactam antibiotic (including cephalosporins, due to possible cross-reactivity)
  • History of liver problems (e.g. jaundice) associated with previous penicillin use
  • Caution required in patients with significant kidney impairment

Drug / Food Interactions

  • Food significantly reduces the absorption of cloxacillin – always take it on an empty stomach
  • Probenecid can increase and prolong cloxacillin blood levels
  • Oral contraceptives may be less reliable during antibiotic treatment – discuss additional contraceptive precautions with your doctor
  • Warfarin’s blood-thinning effect may be enhanced in some patients, requiring closer INR monitoring

Quick Tips

  • Always take on an empty stomach, at least 1 hour before or 2 hours after eating, for the best absorption
  • Complete the full course of antibiotics exactly as prescribed, even if you feel better early
  • Swallow the capsule whole with a full glass of water
  • Tell your doctor if you have had a serious allergic reaction to penicillin or cephalosporin antibiotics in the past
  • Contact your doctor if diarrhoea becomes severe or bloody during treatment
  • Do not share this antibiotic with anyone else, and do not use leftover doses for a different illness

Ingredients / Active Ingredients

  • Cloxacillin 250mg (as cloxacillin sodium)

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Frequently Asked Questions

Product Specifications

BrandPharmaniaga
ClassificationPrescription medicine
Ingredients / Active IngredientsCloxacillin
Pack Size10s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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