Plendil 5mg Tablet
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- Muslim-Friendly
- FDA Approved
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Prescription Required
Overview
Plendil 5mg Tablet contains felodipine 5mg, a dihydropyridine calcium channel blocker used to treat high blood pressure (hypertension), taken as a once-daily extended-release tablet.
Felodipine works by relaxing the smooth muscle in the walls of blood vessels, which widens the vessels and lowers the resistance the heart has to pump against, reducing blood pressure with minimal direct effect on the heart’s own rhythm or pumping strength.
How it Works
Felodipine selectively blocks L-type calcium channels in vascular smooth muscle, reducing calcium entry into these cells. This relaxes and widens the arteries (vasodilation), lowering peripheral resistance and blood pressure, with much less effect on the heart muscle or its electrical conduction compared with non-dihydropyridine calcium channel blockers.
Directions for Use
Take Plendil 5mg Tablet once daily, in the morning, with or without a light meal, but avoid grapefruit or grapefruit juice. Swallow the extended-release tablet whole with water – do not crush, chew, or split it, as this can release the entire dose at once instead of gradually over the day.
Dosage
The usual starting dose of Plendil 5mg Tablet is 5mg once daily, which your doctor may increase up to 10mg daily depending on your blood pressure response. Your doctor will determine the right dose for you and may adjust it gradually.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Headache
- Dizziness or light-headedness
- Flushing (warmth, redness in face)
- Swelling in ankles or feet
- Tiredness or fatigue
- Palpitations (feeling of rapid heartbeat)
- Nausea
Contraindications
- Known hypersensitivity to felodipine or other dihydropyridine calcium channel blockers
- Uncontrolled heart failure
- Unstable angina or the acute phase of a heart attack
- Significant aortic stenosis (use with caution and specialist guidance)
Drug / Food Interactions
- Grapefruit and grapefruit juice significantly increase felodipine blood levels and should be avoided entirely
- CYP3A4 inhibitors such as itraconazole and erythromycin can increase felodipine levels and its blood-pressure-lowering effect
- CYP3A4 inducers such as carbamazepine, phenytoin, and rifampicin can reduce felodipine’s effectiveness
- Other blood pressure medicines may increase the risk of excessively low blood pressure when combined
Quick Tips
- Avoid grapefruit and grapefruit juice completely while on this medicine
- Swallow the tablet whole – never crush, chew, or split it
- Monitor for ankle swelling and report it to your doctor if troublesome
- Maintain good oral hygiene, as calcium channel blockers can occasionally cause gum swelling
Frequently Asked Questions
What is Plendil 5mg Tablet used for?
Plendil 5mg Tablet is used to treat high blood pressure (hypertension), helping to reduce the long-term risk of stroke, heart attack, and kidney problems.
Why must I avoid grapefruit with this medicine?
Grapefruit and grapefruit juice interfere with how the body breaks down felodipine, which can raise its blood levels substantially and increase the risk of side effects like low blood pressure and swelling.
Can I crush or split the tablet if I have trouble swallowing it?
No, this is an extended-release tablet designed to release felodipine gradually over the day. Crushing, chewing, or splitting it can cause the full dose to be released at once, which is unsafe.
Why are my ankles swelling since starting this medicine?
Ankle or leg swelling is a common side effect of felodipine caused by its effect on blood vessels. It is usually not dangerous, but tell your doctor if it is bothersome or severe.
What should I do if I miss a dose of Plendil 5mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue as normal. Do not double the dose.
Can I buy Plendil 5mg Tablet from DoctorOnCall?
Yes, Plendil 5mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Plendil 5mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Plendil 5mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Plendil 5mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Plendil 5mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Plendil 5mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Felodipine 5mg (extended-release)
Safety Advice
Pregnancy
Use during pregnancy is generally not recommended unless absolutely necessary.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Use only if prescribed, with possible monitoring of kidney function.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
