Plendil 2.5mg Tablet
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Prescription Required
Overview
Plendil 2.5mg Tablet contains felodipine 2.5mg in an extended-release formulation, a dihydropyridine calcium channel blocker used to treat high blood pressure (hypertension).
Felodipine works by blocking calcium channels in the smooth muscle of blood vessel walls, preventing calcium from entering these cells. This relaxes and widens blood vessels, lowering blood pressure and reducing the workload on the heart.
How it Works
Felodipine selectively blocks L-type calcium channels in vascular smooth muscle, with little effect on the heart muscle itself. By limiting calcium influx, it relaxes the arterial walls, reducing peripheral vascular resistance and lowering blood pressure in a sustained way over 24 hours due to its extended-release design.
Directions for Use
Take Plendil 2.5mg Tablet once daily, in the morning, with or without food, though a light meal is preferred over a very high-fat meal. Swallow the extended-release tablet whole with a glass of water; do not crush, chew, or split it, as this can release the medicine too quickly. Avoid grapefruit juice while taking this medicine.
Dosage
The usual starting dose of Plendil 2.5mg Tablet is 2.5-5mg once daily, which your doctor may increase up to a maximum of 10mg once daily depending on your blood pressure response. Always take the exact dose prescribed by your doctor, as felodipine is individualised to each patient’s blood pressure control.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Headache
- Dizziness or light-headedness
- Flushing (warmth, redness in face)
- Swelling in ankles or feet
- Tiredness or fatigue
- Palpitations (feeling of rapid heartbeat)
- Nausea
Contraindications
- Known hypersensitivity to felodipine or other dihydropyridine calcium channel blockers
- Unstable angina or within one month of a heart attack
- Severe aortic stenosis (narrowing of the aortic heart valve)
- Severe liver impairment (requires dose adjustment)
Drug / Food Interactions
- Grapefruit juice significantly increases felodipine blood levels and can worsen side effects – avoid it completely while on this medicine
- Strong CYP3A4 inhibitors (e.g. erythromycin, itraconazole, ketoconazole) can raise felodipine levels
- Strong CYP3A4 inducers (e.g. carbamazepine, phenytoin, rifampicin, St John’s Wort) can reduce felodipine’s effectiveness
- Other blood pressure medicines may increase the risk of low blood pressure
Quick Tips
- Swallow the extended-release tablet whole – never crush, chew, or split it
- Completely avoid grapefruit juice and grapefruit products while on this medicine
- Take at the same time each morning to build a consistent routine
- Report new or worsening ankle swelling to your doctor, though this is a common and usually harmless effect
Frequently Asked Questions
What is Plendil 2.5mg Tablet used for?
Plendil 2.5mg Tablet is used to treat high blood pressure by relaxing and widening blood vessels.
Why must I avoid grapefruit juice with this medicine?
Grapefruit juice blocks an enzyme that normally breaks down felodipine, causing much higher levels of the medicine in your blood and increasing the risk of side effects such as low blood pressure and flushing.
Why are my ankles swelling since starting this medicine?
Ankle or foot swelling is a common effect of calcium channel blockers like felodipine, caused by changes in blood vessel pressure rather than fluid retention from the heart or kidneys. Mention it to your doctor if it bothers you or worsens.
Can I crush the tablet if I have trouble swallowing?
No, this extended-release tablet must be swallowed whole. Crushing, chewing, or splitting it can cause the medicine to be released too quickly, increasing the risk of side effects.
What should I do if I miss a dose of Plendil 2.5mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Plendil 2.5mg Tablet from DoctorOnCall?
Yes, Plendil 2.5mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Plendil 2.5mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Plendil 2.5mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Plendil 2.5mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Plendil 2.5mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Plendil 2.5mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Felodipine 2.5mg (extended-release)
Safety Advice
Pregnancy
Use during pregnancy is generally not recommended unless absolutely necessary.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Use only if prescribed, with possible monitoring of kidney function.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
