Plendil 2.5mg Tablet

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Manufacturer AstraZeneca
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Plendil 2.5mg Tablet contains Felodipine 2.5mg (extended-release) and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Plendil 2.5mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take Plendil 2.5mg Tablet once daily, in the morning, with or without food, though a light meal is preferred over a very high-fat meal. Swallow the extended-release tablet whole with a glass of water; do not crush, chew, or split it, as this can release the medicine too quickly. Avoid grapefruit juice while taking this medicine.

Dosage

The usual starting dose of Plendil 2.5mg Tablet is 2.5-5mg once daily, which your doctor may increase up to a maximum of 10mg once daily depending on your blood pressure response. Always take the exact dose prescribed by your doctor, as felodipine is individualised to each patient’s blood pressure control.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Dizziness or light-headedness
  • Flushing (warmth, redness in face)
  • Swelling in ankles or feet
  • Tiredness or fatigue
  • Palpitations (feeling of rapid heartbeat)
  • Nausea

Contraindications

  • Known hypersensitivity to felodipine or other dihydropyridine calcium channel blockers
  • Unstable angina or within one month of a heart attack
  • Severe aortic stenosis (narrowing of the aortic heart valve)
  • Severe liver impairment (requires dose adjustment)

Drug / Food Interactions

  • Grapefruit juice significantly increases felodipine blood levels and can worsen side effects – avoid it completely while on this medicine
  • Strong CYP3A4 inhibitors (e.g. erythromycin, itraconazole, ketoconazole) can raise felodipine levels
  • Strong CYP3A4 inducers (e.g. carbamazepine, phenytoin, rifampicin, St John’s Wort) can reduce felodipine’s effectiveness
  • Other blood pressure medicines may increase the risk of low blood pressure

Quick Tips

  • Swallow the extended-release tablet whole – never crush, chew, or split it
  • Completely avoid grapefruit juice and grapefruit products while on this medicine
  • Take at the same time each morning to build a consistent routine
  • Report new or worsening ankle swelling to your doctor, though this is a common and usually harmless effect

Ingredients / Active Ingredients

  • Felodipine 2.5mg (extended-release)

Safety Advice

Pregnancy

Not Advisable

Use during pregnancy is generally not recommended unless absolutely necessary.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Safe If Prescribed

Use only if prescribed, with possible monitoring of kidney function.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandAstraZeneca
ManufacturerAstraZeneca
ClassificationPrescription medicine
Ingredients / Active IngredientsFelodipine
Pack Size15s, 30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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